Featured Research

from universities, journals, and other organizations

This is what a fish thought looks like

Date:
January 31, 2013
Source:
Cell Press
Summary:
For the first time, researchers have been able to see a thought "swim" through the brain of a living fish. The new technology is a useful tool for studies of perception. It might even find use in psychiatric drug discovery, according to authors of a new study.

For the first time, researchers have been able to see a thought "swim" through the brain of a living fish. The new technology is a useful tool for studies of perception. It might even find use in psychiatric drug discovery, according to authors of the study, appearing online on Jan. 31 in Current Biology, a Cell Press publication.
Credit: Current Biology, Muto et al.

For the first time, researchers have been able to see a thought "swim" through the brain of a living fish. The new technology is a useful tool for studies of perception. It might even find use in psychiatric drug discovery, according to authors of the study, appearing online on January 31 in Current Biology.

"Our work is the first to show brain activities in real time in an intact animal during that animal's natural behavior," said Koichi Kawakami of Japan's National Institute of Genetics. "We can make the invisible visible; that's what is most important."

The technical breakthrough included the development of a very sensitive fluorescent probe to detect neuronal activity. Kawakami, along with Junichi Nakai of Saitama University and their colleagues, also devised a genetic method for inserting that probe right into the neurons of interest. The two-part approach allowed the researchers to detect neuronal activity at single-cell resolution in the zebrafish brain.

Akira Muto, the study's lead author from the Kawakami lab, used the new tool to map what happens when a zebrafish sees something good to eat, in this case a swimming paramecium. The researchers were also able to correlate brain activity with that prey's capture.

The new tool now makes it possible to ask which brain circuits are involved in complex behaviors, from perception to movement to decision making, the researchers say, noting that the basic design and function of a zebrafish brain is very much like our own.

"In the future, we can interpret an animal's behavior, including learning and memory, fear, joy, or anger, based on the activity of particular combinations of neurons," Kawakami said.

By monitoring neuronal activity in the zebrafish brain, Kawakami thinks that researchers may also be able to screen chemicals that affect neuronal activity in the brain. "This has the potential to shorten the long processes for the development of new psychiatric medications," he said.


Story Source:

The above story is based on materials provided by Cell Press. Note: Materials may be edited for content and length.


Journal Reference:

  1. Akira Muto, Masamichi Ohkura, Gembu Abe, Junichi Nakai, Koichi Kawakami. Real-Time Visualization of Neuronal Activity during Perception. Current Biology, 2013; DOI: 10.1016/j.cub.2012.12.040

Cite This Page:

Cell Press. "This is what a fish thought looks like." ScienceDaily. ScienceDaily, 31 January 2013. <www.sciencedaily.com/releases/2013/01/130131144419.htm>.
Cell Press. (2013, January 31). This is what a fish thought looks like. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2013/01/130131144419.htm
Cell Press. "This is what a fish thought looks like." ScienceDaily. www.sciencedaily.com/releases/2013/01/130131144419.htm (accessed April 24, 2014).

Share This



More Mind & Brain News

Thursday, April 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Study Says Most Crime Not Linked To Mental Illness

Study Says Most Crime Not Linked To Mental Illness

Newsy (Apr. 22, 2014) A new study finds most crimes committed by people with mental illness are not caused by symptoms of their illness or disorder. Video provided by Newsy
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com
Do We Get Nicer With Age?

Do We Get Nicer With Age?

Newsy (Apr. 22, 2014) A recent report claims personality can change over time as we age, and usually that means becoming nicer and more emotionally stable. Video provided by Newsy
Powered by NewsLook.com
How to Master Motherhood With the Best Work/Life Balance

How to Master Motherhood With the Best Work/Life Balance

TheStreet (Apr. 22, 2014) In the U.S., there are more than 11 million couples trying to conceive at any given time. From helping celebrity moms like Bethanny Frankel to ordinary soon-to-be-moms, TV personality and parenting expert, Rosie Pope, gives you the inside scoop on mastering motherhood. London-born entrepreneur Pope is the creative force behind Rosie Pope Maternity and MomPrep. She explains why being an entrepreneur offers the best life balance for her and tips for all types of moms. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins