Featured Research

from universities, journals, and other organizations

Diet of resistant starch helps the body resist colorectal cancer

Date:
February 19, 2013
Source:
University of Colorado Denver
Summary:
New research shows that resistant starch helps the body resist colorectal cancer through mechanisms including killing pre-cancerous cells and reducing inflammation that can otherwise promote cancer.

As the name suggests, you can't digest resistant starch so it ends up in the bowel in pretty much the same form it entered your mouth. As unlovely as that seems, once in the bowel this resistant starch does some important things, including decreasing bowel pH and transit time, and increasing the production of short-chain fatty acids. These effects promote the growth of good bugs while keeping bad bugs at bay.

A University of Colorado Cancer Center review published in this month's issue of the journal Current Opinion in Gastroenterology shows that resistant starch also helps the body resist colorectal cancer through mechanisms including killing pre-cancerous cells and reducing inflammation that can otherwise promote cancer.

"Resistant starch is found in peas, beans and other legumes, green bananas, and also in cooked and cooled starchy products like sushi rice and pasta salad. You have to consume it at room temperate or below -- as soon as you heat it, the resistant starch is gone. But consumed correctly, it appears to kill pre-cancerous cells in the bowel," says Janine Higgins, PhD, CU Cancer Center investigator and associate professor of Pediatrics at the University of Colorado School of Medicine.

Higgins describes studies showing that rats fed resistant starch show decreased numbers and sizes of lesions due to colorectal cancer, and an increased number of cells that express the protein IL-10, which acts to regulate the body's inflammatory response.

"Resistant starch may also have implications for the prevention of breast cancer," Higgins says. "For example, if you let rats get obese, get them to lose the weight, and then feed half of the rats a diet high in resistant starch -- these rats don't gain back the weight as fast as rats fed a regular, digestible starch diet. This effect on obesity may help to reduce breast cancer risk as well as having implications for the treatment of colorectal cancer."

"There are a lot of things that feed into the same model of resistant starch as a cancer-protective agent," Higgins says. "Much of this information currently comes from rodent models and small clinical trials but the evidence is encouraging." On the table now is a menu of benefits and while it's just now being studied which benefits, exactly, will pan out as mechanisms of cancer prevention, one thing is clear: resistant starch should be on the menu.


Story Source:

The above story is based on materials provided by University of Colorado Denver. The original article was written by Garth Sundem. Note: Materials may be edited for content and length.


Journal Reference:

  1. Janine A. Higgins, Ian L. Brown. Resistant starch. Current Opinion in Gastroenterology, 2013; 29 (2): 190 DOI: 10.1097/MOG.0b013e32835b9aa3

Cite This Page:

University of Colorado Denver. "Diet of resistant starch helps the body resist colorectal cancer." ScienceDaily. ScienceDaily, 19 February 2013. <www.sciencedaily.com/releases/2013/02/130219140716.htm>.
University of Colorado Denver. (2013, February 19). Diet of resistant starch helps the body resist colorectal cancer. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2013/02/130219140716.htm
University of Colorado Denver. "Diet of resistant starch helps the body resist colorectal cancer." ScienceDaily. www.sciencedaily.com/releases/2013/02/130219140716.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins