Featured Research

from universities, journals, and other organizations

Contact killing of Salmonella by human fecal bacteria

Date:
April 23, 2013
Source:
Norwich BioScience Institutes
Summary:
Researchers have recently found a novel mode of interaction between Salmonella, a foodborne pathogen, and the bacteria that live in our guts. Fecal bacteria collected from healthy donors effectively inactivated Salmonella, when they were allowed close contact. Mathematical modelling of this interaction is now being used to find new ways of controlling Salmonella.

Salmonella and faecal bacteria.
Credit: Kathryn Cross, IFR

Our gut is home to trillions of bacteria, numbering more than the cells in the rest of our body, and these bacteria help us to digest our food, absorb nutrients and strengthen our immune system. This complex bacterial ecosystem, called the gut microbiota, also helps to prevent bad bacteria from colonising our bodies and making us ill.

Related Articles


As part of the symbiotic relationship between the gut microbiota and our bodies, the bacteria derive nutrition from our food and convert it into compounds that we can't make ourselves. Some of these compounds are part of the arsenal that combats harmful bacteria. To date, these are the only identified defense mechanisms associated with gut bacteria.

Dr Carmen Pin, and PhD student Gaspar Avendaρo-Perez at the Institute of Food Research, which is strategically funded by the Biotechnology and Biological Sciences Research Council, have recently found a novel mode of interaction between Salmonella, a foodborne pathogen, and the gut bacteria that leads to the inactivation of Salmonella. This interaction relies on Salmonella and the gut bacteria being in close proximity, or through cell to cell contact. This new way of interaction between the "good" and the" bad" bacteria may contribute to prevent intestinal colonization and infection by foodborne pathogens.

The researchers collected faecal samples from several healthy human donors and used the experimental colon model facility of the Institute of Food Research to culture faecal bacteria together with Salmonella under conditions that mimicked those in the human colon. Gut bacteria effectively inactivated Salmonella in mixed culturesbut only when cell contact between both populations was possible. Salmonella inactivation was not observed when a membrane was included into the system to prevent cell contact between populations.


Story Source:

The above story is based on materials provided by Norwich BioScience Institutes. Note: Materials may be edited for content and length.


Journal Reference:

  1. G. Avendano-Perez, C. Pin. Loss of culturability of Salmonella Typhimurium upon cell-cell contact with human faecal bacteria. Applied and Environmental Microbiology, 2013; DOI: 10.1128/%u200BAEM.00092-13

Cite This Page:

Norwich BioScience Institutes. "Contact killing of Salmonella by human fecal bacteria." ScienceDaily. ScienceDaily, 23 April 2013. <www.sciencedaily.com/releases/2013/04/130423110817.htm>.
Norwich BioScience Institutes. (2013, April 23). Contact killing of Salmonella by human fecal bacteria. ScienceDaily. Retrieved April 19, 2015 from www.sciencedaily.com/releases/2013/04/130423110817.htm
Norwich BioScience Institutes. "Contact killing of Salmonella by human fecal bacteria." ScienceDaily. www.sciencedaily.com/releases/2013/04/130423110817.htm (accessed April 19, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Sunday, April 19, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Un-Bee-Lievable: Bees on the Loose After Washington Truck Crash

Un-Bee-Lievable: Bees on the Loose After Washington Truck Crash

Reuters - US Online Video (Apr. 17, 2015) — A truck carrying honey bees overturns near Lynnwood, Washington, spreading boxes of live bees across the highway. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) — Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Dog Flu Spreading in Midwestern States

Dog Flu Spreading in Midwestern States

AP (Apr. 17, 2015) — Dog flu is spreading in several Midwestern states. Dog daycare centers and veterinary offices are taking precautions. (April 17) Video provided by AP
Powered by NewsLook.com
Raw: Rare Whale Spotted in Gulf of Mexico

Raw: Rare Whale Spotted in Gulf of Mexico

AP (Apr. 17, 2015) — Researchers from the E/V Nautilus had quite a surprise Tuesday, when a curious sperm whale swam around their remotely operated vehicle in the Gulf of Mexico. Cameras captured the encounter. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins