Featured Research

from universities, journals, and other organizations

Electronic stimulation therapy for obstructive sleep apnea is safe, effective, new study suggests

Date:
June 5, 2013
Source:
University Hospitals Case Medical Center
Summary:
A clinical study suggests that electronic stimulation therapy reduces obstructive sleep apnea and is safe and effective. Stimulation Therapy for Apnea Reduction (STAR Trial) evaluated an implantable electronic stimulation device called Inspire Upper Airway Stimulation therapy designed to deliver mild stimulation to the hypoglossal nerve on each breathing cycle during sleep, preventing the tongue from collapsing and obstructing the airway.

A clinical study has found that electronic stimulation therapy to reduce obstructive sleep apnea (OSA) is safe and effective.

Related Articles


The Stimulation Therapy for Apnea Reduction (The STAR Trial) evaluated an implantable electronic stimulation device called Inspire™ Upper Airway Stimulation (UAS) therapy designed to deliver mild stimulation to the main nerve of the tongue (hypoglossal nerve) on each breathing cycle during sleep. The stimulation is intended to restore tone to key airway muscles and prevent airway collapse.

Patients control when the Inspire therapy is turned on and off using a handheld programmer. In contrast to other surgical procedures to treat sleep apnea, Inspire therapy does not require removing or permanently altering an OSA patient's facial or airway anatomy.

"Studies have shown that sleep apnea is as prevalent as adult diabetes and asthma and the consequences of OSA range from disruptive to life-threatening," said Kingman Strohl, MD, principal investigator for the University Hospitals (UH) Case Medical Center site. "While many patients have found help with continuous positive air pressure through a CPAP nasal mask, for some patients it is too difficult to comply with, and thus ineffective," he said.

The primary aim of this study was to determine the safety and efficacy of the stimulation for treatment of OSA.

Results were presented on June 5 at Sleep 2013, 27th Annual Meeting of the Associated Professional Sleep Societies, by Dr. Strohl, who also is professor of medicine at Case Western Reserve University School of Medicine, and colleagues Patrick Strollo, MD, and Ryan Soose, MD, both of the University of Pittsburgh School of Medicine.

The multi-center study had 126 participants (21 females) who received an implanted system. At 12 months, there was a significant reduction in the Apnea Hypopnea Index (AHI) and Oxygen Desaturation Index, two scales used to indicate the severity of OSA. There also were significant improvements from pre-implant to 12 months on sleep quality scales (Epworth Sleepiness Scale, ESS, and Functional Outcome of Sleep Questionnaire, FOSQ).

More than 18 million Americans suffer from OSA, which is characterized by repeated episodes of upper airway collapse during sleep. Patients with OSA stop breathing frequently during sleep, often for a minute or longer. Daytime sleepiness, depression, weight gain, increase in industrial accidents and diminished quality of life are all commonly observed in people who suffer from OSA as a result of fragmented sleep patterns.

Dr. Strohl said the STAR trial data has been submitted to the FDA for review and consideration for approval.


Story Source:

The above story is based on materials provided by University Hospitals Case Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

University Hospitals Case Medical Center. "Electronic stimulation therapy for obstructive sleep apnea is safe, effective, new study suggests." ScienceDaily. ScienceDaily, 5 June 2013. <www.sciencedaily.com/releases/2013/06/130605144316.htm>.
University Hospitals Case Medical Center. (2013, June 5). Electronic stimulation therapy for obstructive sleep apnea is safe, effective, new study suggests. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2013/06/130605144316.htm
University Hospitals Case Medical Center. "Electronic stimulation therapy for obstructive sleep apnea is safe, effective, new study suggests." ScienceDaily. www.sciencedaily.com/releases/2013/06/130605144316.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins