Featured Research

from universities, journals, and other organizations

Probiotics do not prevent relapse in Crohn's disease patients

Date:
August 14, 2013
Source:
American Gastroenterological Association
Summary:
Despite previous data showing beneficial effects, the probiotic Saccharomuces boulardii does not prevent clinical relapse in patients with Crohn's disease.

Despite previous data showing beneficial effects, the probiotic Saccharomuces boulardii (S. boulardii) does not prevent clinical relapse in patients with Crohn's disease, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

As more people seek natural or non-drug ways to maintain their health, products containing probiotics have flooded the marketplace. While safe and tolerable, this study discovered that the probiotic S. boulardii does not appear to have any significant beneficial effects for patients with Crohn's disease who are already in remission.

In this randomized, double-blind, placebo-controlled trial, the probiotic yeast S. boulardii was tested as a preventive therapy in patients with moderately severe Crohn's disease who were currently in remission following steroid or salicylate therapies. At the end of the one-year follow-up period, 50 percent of patients had relapsed -- 47.5 percent in the S. boulardii group and, similarly, 53.2 percent in the placebo group. Further, the time-to-relapse was not statistically different between patients treated with S. boulardii or placebo.

While this probiotic showed no positive effects for Crohn's disease patients, further studies are needed to determine the potential therapeutic efficacy of probiotics in other forms of IBD, such as ulcerative colitis, and pouchitis.

Probiotics are living microscopic organisms, or microorganisms, that scientific research has shown to benefit an individual's health. S. boulardii, a probiotic made from a strain of yeast and sold in local drug stores or supermarkets in the form of capsules, has been demonstrated to be effective in the treatment of traveler's diarrhea, diarrhea occurring in subjects infected with the human immunodeficiency virus and the prevention of diarrhea associated with antibiotics.


Story Source:

The above story is based on materials provided by American Gastroenterological Association. Note: Materials may be edited for content and length.


Journal Reference:

  1. Arnaud Bourreille, Guillaume Cadiot, Gιrard Le Dreau, David Laharie, Laurent Beaugerie, Jean–Louis Dupas, Philippe Marteau, Patrick Rampal, Dominique Moyse, Ashraf Saleh, Marie–Emmanuelle Le Guern, Jean–Paul Galmiche. Saccharomyces boulardii Does Not Prevent Relapse of Crohn's Disease. Clinical Gastroenterology and Hepatology, 2013; 11 (8): 982 DOI: 10.1016/j.cgh.2013.02.021

Cite This Page:

American Gastroenterological Association. "Probiotics do not prevent relapse in Crohn's disease patients." ScienceDaily. ScienceDaily, 14 August 2013. <www.sciencedaily.com/releases/2013/08/130814124738.htm>.
American Gastroenterological Association. (2013, August 14). Probiotics do not prevent relapse in Crohn's disease patients. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2013/08/130814124738.htm
American Gastroenterological Association. "Probiotics do not prevent relapse in Crohn's disease patients." ScienceDaily. www.sciencedaily.com/releases/2013/08/130814124738.htm (accessed September 22, 2014).

Share This



More Health & Medicine News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) — Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) — Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) — A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) — The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins