Featured Research

from universities, journals, and other organizations

Natural compound can be used for 3-D printing of medical implants

Date:
October 23, 2013
Source:
North Carolina State University
Summary:
Biomedical engineering researchers have discovered that a naturally-occurring compound can be incorporated into three-dimensional printing processes to create medical implants out of non-toxic polymers. The compound is riboflavin, which is better known as vitamin B2.

The discovery enables researchers to create finely-detailed, biocompatible structures, such as this scaffold for tissue engineering.
Credit: Regen. Med. 8(6), 725–738 (2013).

Researchers from North Carolina State University, the University of North Carolina at Chapel Hill and Laser Zentrum Hannover have discovered that a naturally-occurring compound can be incorporated into three-dimensional (3-D) printing processes to create medical implants out of non-toxic polymers. The compound is riboflavin, which is better known as vitamin B2.

"This opens the door to a much wider range of biocompatible implant materials, which can be used to develop customized implant designs using 3-D printing technology," says Dr. Roger Narayan, senior author of a paper describing the work and a professor in the joint biomedical engineering department at NC State and UNC-Chapel Hill.

The researchers in this study focused on a 3-D printing technique called two-photon polymerization, because this technique can be used to create small objects with detailed features -- such as scaffolds for tissue engineering, microneedles or other implantable drug-delivery devices.

Two-photon polymerization is a 3-D printing technique for making small-scale solid structures from many types of photoreactive liquid precursors. The liquid precursors contain chemicals that react to light, turning the liquid into a solid polymer. By exposing the liquid precursor to targeted amounts of light, the technique allows users to "print" 3-D objects.

Two-photon polymerization has its drawbacks, however. Most chemicals mixed into the precursors to make them photoreactive are also toxic, which could be problematic if the structures are used in a medical implant or are in direct contact with the body.

But now researchers have determined that riboflavin can be mixed with a precursor material to make it photoreactive. And riboflavin is both nontoxic and biocompatible -- it's a vitamin found in everything from asparagus to cottage cheese.


Story Source:

The above story is based on materials provided by North Carolina State University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Alexander K Nguyen, Shaun D Gittard, Anastasia Koroleva, Sabrina Schlie, Arune Gaidukeviciute, Boris N Chichkov, Roger J Narayan. Two-photon polymerization of polyethylene glycol diacrylate scaffolds with riboflavin and triethanolamine used as a water-soluble photoinitiator. Regenerative Medicine, 2013; 8 (6): 725 DOI: 10.2217/rme.13.60

Cite This Page:

North Carolina State University. "Natural compound can be used for 3-D printing of medical implants." ScienceDaily. ScienceDaily, 23 October 2013. <www.sciencedaily.com/releases/2013/10/131023101326.htm>.
North Carolina State University. (2013, October 23). Natural compound can be used for 3-D printing of medical implants. ScienceDaily. Retrieved October 22, 2014 from www.sciencedaily.com/releases/2013/10/131023101326.htm
North Carolina State University. "Natural compound can be used for 3-D printing of medical implants." ScienceDaily. www.sciencedaily.com/releases/2013/10/131023101326.htm (accessed October 22, 2014).

Share This



More Matter & Energy News

Wednesday, October 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Thanks, Marty McFly! Hoverboards Could Be Coming In 2015

Thanks, Marty McFly! Hoverboards Could Be Coming In 2015

Newsy (Oct. 21, 2014) If you've ever watched "Back to the Future Part II" and wanted to get your hands on a hoverboard, well, you might soon be in luck. Video provided by Newsy
Powered by NewsLook.com
Robots to Fly Planes Where Humans Can't

Robots to Fly Planes Where Humans Can't

Reuters - Innovations Video Online (Oct. 21, 2014) Researchers in South Korea are developing a robotic pilot that could potentially replace humans in the cockpit. Unlike drones and autopilot programs which are configured for specific aircraft, the robots' humanoid design will allow it to fly any type of plane with no additional sensors. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
Graphene Paint Offers Rust-Free Future

Graphene Paint Offers Rust-Free Future

Reuters - Innovations Video Online (Oct. 21, 2014) British scientists have developed a prototype graphene paint that can make coatings which are resistant to liquids, gases, and chemicals. The team says the paint could have a variety of uses, from stopping ships rusting to keeping food fresher for longer. Jim Drury reports. Video provided by Reuters
Powered by NewsLook.com
China Airlines Swanky New Plane

China Airlines Swanky New Plane

Buzz60 (Oct. 21, 2014) China Airlines debuted their new Boeing 777, and it's more like a swanky hotel bar than an airplane. Enjoy high-tea, a coffee bar, and a full service bar with cocktails and spirits, and lie-flat in your reclining seats. Sean Dowling (@SeanDowlingTV) has the details. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins