Featured Research

from universities, journals, and other organizations

Protein illustrates muscle damage

Date:
November 11, 2013
Source:
McMaster University
Summary:
Regardless of the way in which muscle was damaged, either through trauma or disease, the protein called Xin was strongly correlated to the degree of damage.

Researchers at McMaster University have discovered a protein that is only detectable after muscle damage, and it may serve as a way to measure injury.

“Our results highlight the protein called Xin as a muscle damage biomarker,” said Thomas Hawke, principal investigator and an associate professor for the Department of Pathology and Molecular Medicine at McMaster.

“Regardless of the way in which muscle was damaged, either through trauma or disease, Xin was strongly correlated to the degree of damage.”

The research will be published in the December issue of The American Journal of Pathology.

The paper explains that the protein Xin is undetectable in muscle biopsies of healthy subjects. However, when muscle damage occurs, Xin becomes detectable and shows a pattern that highly correlates with the amount of muscle damage.

The researchers found this to be true for healthy subjects who have damaged their muscles with intense exercise as well as numerous patients with various forms of muscle disease, including muscular dystrophy.


Story Source:

The above story is based on materials provided by McMaster University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Mats I. Nilsson, Aliyah A. Nissar, Dhuha Al-Sajee, Mark A. Tarnopolsky, Gianni Parise, Boleslav Lach, Dieter O. Fόrst, Peter F.M. van der Ven, Rudolf A. Kley, Thomas J. Hawke. Xin Is a Marker of Skeletal Muscle Damage Severity in Myopathies. The American Journal of Pathology, 2013; DOI: 10.1016/j.ajpath.2013.08.010

Cite This Page:

McMaster University. "Protein illustrates muscle damage." ScienceDaily. ScienceDaily, 11 November 2013. <www.sciencedaily.com/releases/2013/11/131111161241.htm>.
McMaster University. (2013, November 11). Protein illustrates muscle damage. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2013/11/131111161241.htm
McMaster University. "Protein illustrates muscle damage." ScienceDaily. www.sciencedaily.com/releases/2013/11/131111161241.htm (accessed April 24, 2014).

Share This



More Health & Medicine News

Thursday, April 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Fungus Killing Bats, Spreading in US

Deadly Fungus Killing Bats, Spreading in US

AP (Apr. 24, 2014) — A disease that has killed more than six million cave-dwelling bats in the United States is on the move and wildlife biologists are worried. White Nose Syndrome, discovered in New York in 2006, has now spread to 25 states. (April 24) Video provided by AP
Powered by NewsLook.com
Companies Ramp Up Wellness to Lower Health Costs

Companies Ramp Up Wellness to Lower Health Costs

AP (Apr. 24, 2014) — That little voice telling you to exercise, get in shape and get healthy is probably coming from your boss. More companies are beefing up wellness programs to try and cut down their health care costs. (April 24) Video provided by AP
Powered by NewsLook.com
FDA Wants To Ban Sales Of E-Cigarettes To Minors

FDA Wants To Ban Sales Of E-Cigarettes To Minors

Newsy (Apr. 24, 2014) — The Food and Drug Administration wants to crack down on the use of e-cigarettes, banning the sale of the product to minors. Video provided by Newsy
Powered by NewsLook.com
Michigan Man Sees Thanks to 'bionic Eye'

Michigan Man Sees Thanks to 'bionic Eye'

AP (Apr. 23, 2014) — A legally blind Michigan man is 'seeing something new every day' thanks to a high-tech retinal implant procedure. He's one of the first in the country to receive a 'bionic eye' since the federal government approved the surgery. (April 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins