Featured Research

from universities, journals, and other organizations

Protein illustrates muscle damage

Date:
November 11, 2013
Source:
McMaster University
Summary:
Regardless of the way in which muscle was damaged, either through trauma or disease, the protein called Xin was strongly correlated to the degree of damage.

Researchers at McMaster University have discovered a protein that is only detectable after muscle damage, and it may serve as a way to measure injury.

Related Articles


“Our results highlight the protein called Xin as a muscle damage biomarker,” said Thomas Hawke, principal investigator and an associate professor for the Department of Pathology and Molecular Medicine at McMaster.

“Regardless of the way in which muscle was damaged, either through trauma or disease, Xin was strongly correlated to the degree of damage.”

The research will be published in the December issue of The American Journal of Pathology.

The paper explains that the protein Xin is undetectable in muscle biopsies of healthy subjects. However, when muscle damage occurs, Xin becomes detectable and shows a pattern that highly correlates with the amount of muscle damage.

The researchers found this to be true for healthy subjects who have damaged their muscles with intense exercise as well as numerous patients with various forms of muscle disease, including muscular dystrophy.


Story Source:

The above story is based on materials provided by McMaster University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Mats I. Nilsson, Aliyah A. Nissar, Dhuha Al-Sajee, Mark A. Tarnopolsky, Gianni Parise, Boleslav Lach, Dieter O. Fόrst, Peter F.M. van der Ven, Rudolf A. Kley, Thomas J. Hawke. Xin Is a Marker of Skeletal Muscle Damage Severity in Myopathies. The American Journal of Pathology, 2013; DOI: 10.1016/j.ajpath.2013.08.010

Cite This Page:

McMaster University. "Protein illustrates muscle damage." ScienceDaily. ScienceDaily, 11 November 2013. <www.sciencedaily.com/releases/2013/11/131111161241.htm>.
McMaster University. (2013, November 11). Protein illustrates muscle damage. ScienceDaily. Retrieved January 25, 2015 from www.sciencedaily.com/releases/2013/11/131111161241.htm
McMaster University. "Protein illustrates muscle damage." ScienceDaily. www.sciencedaily.com/releases/2013/11/131111161241.htm (accessed January 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, January 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Mistakes Should Serve a Lesson Says WHO

Ebola Mistakes Should Serve a Lesson Says WHO

AFP (Jan. 25, 2015) — The World Health Organization&apos;s chief on Sunday admitted the UN agency had been caught napping on Ebola, saying it should serve a lesson to avoid similar mistakes in future. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) — Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) — Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) — A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins