Featured Research

from universities, journals, and other organizations

Protein illustrates muscle damage

Date:
November 11, 2013
Source:
McMaster University
Summary:
Regardless of the way in which muscle was damaged, either through trauma or disease, the protein called Xin was strongly correlated to the degree of damage.

Researchers at McMaster University have discovered a protein that is only detectable after muscle damage, and it may serve as a way to measure injury.

“Our results highlight the protein called Xin as a muscle damage biomarker,” said Thomas Hawke, principal investigator and an associate professor for the Department of Pathology and Molecular Medicine at McMaster.

“Regardless of the way in which muscle was damaged, either through trauma or disease, Xin was strongly correlated to the degree of damage.”

The research will be published in the December issue of The American Journal of Pathology.

The paper explains that the protein Xin is undetectable in muscle biopsies of healthy subjects. However, when muscle damage occurs, Xin becomes detectable and shows a pattern that highly correlates with the amount of muscle damage.

The researchers found this to be true for healthy subjects who have damaged their muscles with intense exercise as well as numerous patients with various forms of muscle disease, including muscular dystrophy.


Story Source:

The above story is based on materials provided by McMaster University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Mats I. Nilsson, Aliyah A. Nissar, Dhuha Al-Sajee, Mark A. Tarnopolsky, Gianni Parise, Boleslav Lach, Dieter O. Fόrst, Peter F.M. van der Ven, Rudolf A. Kley, Thomas J. Hawke. Xin Is a Marker of Skeletal Muscle Damage Severity in Myopathies. The American Journal of Pathology, 2013; DOI: 10.1016/j.ajpath.2013.08.010

Cite This Page:

McMaster University. "Protein illustrates muscle damage." ScienceDaily. ScienceDaily, 11 November 2013. <www.sciencedaily.com/releases/2013/11/131111161241.htm>.
McMaster University. (2013, November 11). Protein illustrates muscle damage. ScienceDaily. Retrieved September 1, 2014 from www.sciencedaily.com/releases/2013/11/131111161241.htm
McMaster University. "Protein illustrates muscle damage." ScienceDaily. www.sciencedaily.com/releases/2013/11/131111161241.htm (accessed September 1, 2014).

Share This




More Health & Medicine News

Monday, September 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) — A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Liberia Continues Fight Against Ebola

Liberia Continues Fight Against Ebola

AFP (Aug. 30, 2014) — Authorities in Liberia try to stem the spread of the Ebola epidemic by raising awareness and setting up sanitation units for people to wash their hands. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

Reuters - US Online Video (Aug. 30, 2014) — California lawmakers pass a bill requiring universities to adopt "affirmative consent" language in their definitions of consensual sex, part of a nationwide drive to curb sexual assault on campuses. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
New Drug Could Reduce Cardiovascular Deaths

New Drug Could Reduce Cardiovascular Deaths

Newsy (Aug. 30, 2014) — The new drug from Novartis could reduce cardiovascular deaths by 20 percent compared to other similar drugs. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins