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First plant-based 'microswimmers' could propel drugs to the right location

Date:
December 18, 2013
Source:
American Chemical Society
Summary:
In the quest to shrink motors so they can maneuver in tiny spaces like inside and between human cells, scientists have taken inspiration from millions of years of plant evolution and incorporated, for the first time, corkscrew structures from plants into a new kind of helical "microswimmer." The low-cost development could be used on a large scale in targeted drug delivery and other applications.

In the quest to shrink motors so they can maneuver in tiny spaces like inside and between human cells, scientists have taken inspiration from millions of years of plant evolution and incorporated, for the first time, corkscrew structures from plants into a new kind of helical "microswimmer." The low-cost development, which appears in ACS' journal Nano Letters, could be used on a large scale in targeted drug delivery and other applications

Joseph Wang and colleagues point out that nanomotors have tremendous potential in diverse applications from delivering drugs to precise locations in the body to making biosensors. To realize this potential, scientists have recently taken inspiration from microorganisms that have tiny, hair-like structures that they whip around to propel themselves. But copying these nature-engineered nanomotors requires advanced instruments and costly processing techniques that make them a challenge to produce on a large scale. To address these issues of practicality, Wang's group also drew inspiration from nature, but turned to plants instead.

They isolated spiral microstructures packed by the million in small pieces of a plant's stem. The scientists coated these tiny coils that are about the width of a fine cotton fiber with thin layers of titanium and magnetic nickel. The plant material makes these microswimmers biodegradable and less likely to be rejected by the human body. The magnetic layer allows scientists to control the motors' movement. When the scientists placed the coated spirals in water or human blood serum and applied a magnetic field, the nanomotors efficiently spun their way through the liquids. The scientists conclude that the microswimmers show great promise for future biomedical uses.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Wei Gao, Xiaomiao Feng, Allen Pei, Christopher R. Kane, Ryan Tam, Camille Hennessy, Joseph Wang. Bioinspired Helical Microswimmers Based on Vascular Plants. Nano Letters, 2013; 131206082414002 DOI: 10.1021/nl404044d

Cite This Page:

American Chemical Society. "First plant-based 'microswimmers' could propel drugs to the right location." ScienceDaily. ScienceDaily, 18 December 2013. <www.sciencedaily.com/releases/2013/12/131218112958.htm>.
American Chemical Society. (2013, December 18). First plant-based 'microswimmers' could propel drugs to the right location. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/2013/12/131218112958.htm
American Chemical Society. "First plant-based 'microswimmers' could propel drugs to the right location." ScienceDaily. www.sciencedaily.com/releases/2013/12/131218112958.htm (accessed September 18, 2014).

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