Featured Research

from universities, journals, and other organizations

Microbiota in late second and early third trimester differs in women who go on to have preterm birth

Date:
February 3, 2014
Source:
Society for Maternal-Fetal Medicine
Summary:
Cervicovaginal microbiota differs in the late second and early third trimester in women destined to have a preterm birth.

In a study to be presented on Feb. 6 at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in New Orleans, researchers will report that cervicovaginal (CV) microbiota differs in the late second and early third trimester in women destined to have a preterm birth.

Related Articles


The study tested vaginal swabs from pregnant women in the late second trimester (20-24 weeks) and early third trimester (24-28) weeks of pregnancy, and compared the CV biospecimens of women who ultimately had a preterm birth to those who had a term birth.

Using DNA obtained on those swabs, the microbial communities were characterized by community state types (CSTs) using state-of-the-art technology. CST I are dominated by Lactobacillus crispatus, traditionally considered a beneficial bacteria. CST III are dominated by Lactobacillus iners, and CST IV are dominated by anaerobic bacteria normally considered to contribute to the condition of bacterial vaginosis.

"We compared the proportion of CSTs in the women who ultimately had a preterm birth to those who had a term birth," said Michal Elovitz, M.D. "The percent of non-CST III was significantly lower in samples from women delivering preterm than term. Notably, the differences in these microbial communities were evident in the late second trimester of pregnancy, weeks if not months prior to the preterm birth."

Elovitz, director of the Maternal and Child Health Research Program at the Perelman School of Medicine at the University of Pennsylvania, said that further research is required to find out how these different microbial communities contribute to preterm birth. "This study is the first to report such key differences in the CV microbial communities weeks prior to preterm birth. If differences in the CV microbial communities are confirmed, then new and exciting therapeutic strategies will emerge to prevent preterm birth."

With funding from the National Institute of Nursing Research, Elovitz confirmed that the team of researchers on this study is currently pursuing a large prospective cohort to further understand the role of CV microbial communities in preterm birth.


Story Source:

The above story is based on materials provided by Society for Maternal-Fetal Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Society for Maternal-Fetal Medicine. "Microbiota in late second and early third trimester differs in women who go on to have preterm birth." ScienceDaily. ScienceDaily, 3 February 2014. <www.sciencedaily.com/releases/2014/02/140203084250.htm>.
Society for Maternal-Fetal Medicine. (2014, February 3). Microbiota in late second and early third trimester differs in women who go on to have preterm birth. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2014/02/140203084250.htm
Society for Maternal-Fetal Medicine. "Microbiota in late second and early third trimester differs in women who go on to have preterm birth." ScienceDaily. www.sciencedaily.com/releases/2014/02/140203084250.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins