Featured Research

from universities, journals, and other organizations

Microbiota in late second and early third trimester differs in women who go on to have preterm birth

Date:
February 3, 2014
Source:
Society for Maternal-Fetal Medicine
Summary:
Cervicovaginal microbiota differs in the late second and early third trimester in women destined to have a preterm birth.

In a study to be presented on Feb. 6 at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in New Orleans, researchers will report that cervicovaginal (CV) microbiota differs in the late second and early third trimester in women destined to have a preterm birth.

The study tested vaginal swabs from pregnant women in the late second trimester (20-24 weeks) and early third trimester (24-28) weeks of pregnancy, and compared the CV biospecimens of women who ultimately had a preterm birth to those who had a term birth.

Using DNA obtained on those swabs, the microbial communities were characterized by community state types (CSTs) using state-of-the-art technology. CST I are dominated by Lactobacillus crispatus, traditionally considered a beneficial bacteria. CST III are dominated by Lactobacillus iners, and CST IV are dominated by anaerobic bacteria normally considered to contribute to the condition of bacterial vaginosis.

"We compared the proportion of CSTs in the women who ultimately had a preterm birth to those who had a term birth," said Michal Elovitz, M.D. "The percent of non-CST III was significantly lower in samples from women delivering preterm than term. Notably, the differences in these microbial communities were evident in the late second trimester of pregnancy, weeks if not months prior to the preterm birth."

Elovitz, director of the Maternal and Child Health Research Program at the Perelman School of Medicine at the University of Pennsylvania, said that further research is required to find out how these different microbial communities contribute to preterm birth. "This study is the first to report such key differences in the CV microbial communities weeks prior to preterm birth. If differences in the CV microbial communities are confirmed, then new and exciting therapeutic strategies will emerge to prevent preterm birth."

With funding from the National Institute of Nursing Research, Elovitz confirmed that the team of researchers on this study is currently pursuing a large prospective cohort to further understand the role of CV microbial communities in preterm birth.


Story Source:

The above story is based on materials provided by Society for Maternal-Fetal Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Society for Maternal-Fetal Medicine. "Microbiota in late second and early third trimester differs in women who go on to have preterm birth." ScienceDaily. ScienceDaily, 3 February 2014. <www.sciencedaily.com/releases/2014/02/140203084250.htm>.
Society for Maternal-Fetal Medicine. (2014, February 3). Microbiota in late second and early third trimester differs in women who go on to have preterm birth. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2014/02/140203084250.htm
Society for Maternal-Fetal Medicine. "Microbiota in late second and early third trimester differs in women who go on to have preterm birth." ScienceDaily. www.sciencedaily.com/releases/2014/02/140203084250.htm (accessed August 20, 2014).

Share This




More Health & Medicine News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com
101-Year-Old Working Man Has All The Advice You Need

101-Year-Old Working Man Has All The Advice You Need

Newsy (Aug. 19, 2014) Herman Goldman has worked at the same lighting store for almost 75 years. Find out his secrets to a happy, productive life. Video provided by Newsy
Powered by NewsLook.com
Researcher Testing on-Field Concussion Scanners

Researcher Testing on-Field Concussion Scanners

AP (Aug. 19, 2014) Four Texas high school football programs are trying out an experimental system designed to diagnose concussions on the field. The technology is in response to growing concern over head trauma in America's most watched sport. (Aug. 19) Video provided by AP
Powered by NewsLook.com
American Ebola Patient Apparently Improving, Outbreak Is Not

American Ebola Patient Apparently Improving, Outbreak Is Not

Newsy (Aug. 19, 2014) Nancy Writebol, an American missionary who contracted Ebola, is apparently getting better, according to her husband. The outbreak, however, is not. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins