Featured Research

from universities, journals, and other organizations

Consuming probiotics for a month helps diminish fat accumulation in the liver, according to a new study

Date:
July 18, 2014
Source:
University of Granada
Summary:
Scientists have demonstrated through an experiment on obese rats that the consumption of probiotics for thirty days helps diminish the accumulation of fat in the liver. This new findingis a step forward on the fight against Non-Alcolohic Fatty Liver Disease (NAFLD), which is closely related to obesity and diabetes.

Spanish scientists have demonstrated through an experiment on obese rats that the consumption of probiotics for thirty days helps diminish the accumulation of fat in the liver. This new finding, recently published by the journal PLOS ONE, is a step forward on the fight against Non-Alcolohic Fatty Liver Disease (NAFLD), which is closely related to obesity and diabetes.

Related Articles


Researchers from the 'Nutrition Biochemistry: Theurapetic Applications' group (CTS-461) and the José Mataix Institute for Nutrition and Food Technology at the University of Granada have demonstrated that the administration of three probiotic strains diminishes the accumulation of fat in the liver of obese rats.

The accumulation of fat in the liver is called steatosis and it constitutes the first stage in the NAFLD disease, which is closely related to obesity and diabetes. Given that the prevalence of these two pathologies, NAFLD has also become a health problem that affects millions of people throughout the world.

Living or dead microorganisms

Probiotics are microorganisms (bacteria or yeasts) with healthy effects upon individuals that consume them in adequate doses. They were traditionally considered to be living microorganisms, but the concept was widened since some dead microorganisms, or even their components, can display probiotic properties.

University of Granada researchers worked with three strains from the Collection Nationale de Cultures de Microorganismes (CNCM) of the Pasteur Institute: Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036. During their first experiment, conducted on healthy volunteers, researchers demonstrated that all three of them are tolerable and safe for human consumption.

In this current study, the strains were administered during thirty days in the diet of Zucker rats. These rats develop obesity due to a mutation in the gene that codifies the receptor or leptin, a homone that transmits a sensation of satiety to the organism. Zucker rats are among the best characterized genetic models.

In their article, the authors describe that the administration of probiotics led to an accumulation of lipids (most of them triacylglycerides) in the liver which was significantly lower than that occurring in rats fed with a placebo.

"This new finding went hand in hand with lower values in proinflamatory molecules (tumor-a necrosis factor, interleukin 6 and liposacarid) in the serum of rats fed with probiotics.

According to these researchers, this liver disease will not be cured with probiotics, but these microorganisms can certainly be used as support therapy in joint use with other treatments.

This study has been financed by the private company HERO SPAIN S.A.


Story Source:

The above story is based on materials provided by University of Granada. Note: Materials may be edited for content and length.


Journal Reference:

  1. Julio Plaza-Diaz, Carolina Gomez-Llorente, Francisco Abadia-Molina, Maria Jose Saez-Lara, Laura Campaña-Martin, Sergio Muñoz-Quezada, Fernando Romero, Angel Gil, Luis Fontana. Effects of Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036 on Hepatic Steatosis in Zucker Rats. PLoS ONE, 2014; 9 (5): e98401 DOI: 10.1371/journal.pone.0098401

Cite This Page:

University of Granada. "Consuming probiotics for a month helps diminish fat accumulation in the liver, according to a new study." ScienceDaily. ScienceDaily, 18 July 2014. <www.sciencedaily.com/releases/2014/07/140718095645.htm>.
University of Granada. (2014, July 18). Consuming probiotics for a month helps diminish fat accumulation in the liver, according to a new study. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2014/07/140718095645.htm
University of Granada. "Consuming probiotics for a month helps diminish fat accumulation in the liver, according to a new study." ScienceDaily. www.sciencedaily.com/releases/2014/07/140718095645.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Christmas Kissing Good for Health

Christmas Kissing Good for Health

Reuters - Innovations Video Online (Dec. 22, 2014) — Scientists in Amsterdam say couples transfer tens of millions of microbes when they kiss, encouraging healthy exposure to bacteria. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Brain-Dwelling Tapeworm Reveals Genetic Secrets

Brain-Dwelling Tapeworm Reveals Genetic Secrets

Reuters - Innovations Video Online (Dec. 22, 2014) — Cambridge scientists have unravelled the genetic code of a rare tapeworm that lived inside a patient's brain for at least four year. Researchers hope it will present new opportunities to diagnose and treat this invasive parasite. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) — A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) — Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins