Featured Research

from universities, journals, and other organizations

Consuming probiotics for a month helps diminish fat accumulation in the liver, according to a new study

Date:
July 18, 2014
Source:
University of Granada
Summary:
Scientists have demonstrated through an experiment on obese rats that the consumption of probiotics for thirty days helps diminish the accumulation of fat in the liver. This new findingis a step forward on the fight against Non-Alcolohic Fatty Liver Disease (NAFLD), which is closely related to obesity and diabetes.

Spanish scientists have demonstrated through an experiment on obese rats that the consumption of probiotics for thirty days helps diminish the accumulation of fat in the liver. This new finding, recently published by the journal PLOS ONE, is a step forward on the fight against Non-Alcolohic Fatty Liver Disease (NAFLD), which is closely related to obesity and diabetes.

Related Articles


Researchers from the 'Nutrition Biochemistry: Theurapetic Applications' group (CTS-461) and the José Mataix Institute for Nutrition and Food Technology at the University of Granada have demonstrated that the administration of three probiotic strains diminishes the accumulation of fat in the liver of obese rats.

The accumulation of fat in the liver is called steatosis and it constitutes the first stage in the NAFLD disease, which is closely related to obesity and diabetes. Given that the prevalence of these two pathologies, NAFLD has also become a health problem that affects millions of people throughout the world.

Living or dead microorganisms

Probiotics are microorganisms (bacteria or yeasts) with healthy effects upon individuals that consume them in adequate doses. They were traditionally considered to be living microorganisms, but the concept was widened since some dead microorganisms, or even their components, can display probiotic properties.

University of Granada researchers worked with three strains from the Collection Nationale de Cultures de Microorganismes (CNCM) of the Pasteur Institute: Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036. During their first experiment, conducted on healthy volunteers, researchers demonstrated that all three of them are tolerable and safe for human consumption.

In this current study, the strains were administered during thirty days in the diet of Zucker rats. These rats develop obesity due to a mutation in the gene that codifies the receptor or leptin, a homone that transmits a sensation of satiety to the organism. Zucker rats are among the best characterized genetic models.

In their article, the authors describe that the administration of probiotics led to an accumulation of lipids (most of them triacylglycerides) in the liver which was significantly lower than that occurring in rats fed with a placebo.

"This new finding went hand in hand with lower values in proinflamatory molecules (tumor-a necrosis factor, interleukin 6 and liposacarid) in the serum of rats fed with probiotics.

According to these researchers, this liver disease will not be cured with probiotics, but these microorganisms can certainly be used as support therapy in joint use with other treatments.

This study has been financed by the private company HERO SPAIN S.A.


Story Source:

The above story is based on materials provided by University of Granada. Note: Materials may be edited for content and length.


Journal Reference:

  1. Julio Plaza-Diaz, Carolina Gomez-Llorente, Francisco Abadia-Molina, Maria Jose Saez-Lara, Laura Campaña-Martin, Sergio Muñoz-Quezada, Fernando Romero, Angel Gil, Luis Fontana. Effects of Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036 on Hepatic Steatosis in Zucker Rats. PLoS ONE, 2014; 9 (5): e98401 DOI: 10.1371/journal.pone.0098401

Cite This Page:

University of Granada. "Consuming probiotics for a month helps diminish fat accumulation in the liver, according to a new study." ScienceDaily. ScienceDaily, 18 July 2014. <www.sciencedaily.com/releases/2014/07/140718095645.htm>.
University of Granada. (2014, July 18). Consuming probiotics for a month helps diminish fat accumulation in the liver, according to a new study. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2014/07/140718095645.htm
University of Granada. "Consuming probiotics for a month helps diminish fat accumulation in the liver, according to a new study." ScienceDaily. www.sciencedaily.com/releases/2014/07/140718095645.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins