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New strategy can help determine heart attack in patients within one hour

Date:
April 13, 2015
Source:
Canadian Medical Association Journal
Summary:
A new strategy to rule-out and rule-in heart attacks in emergency departments will help physicians treat patients faster, found a clinical trial. Acute myocardial infarction (MI) is a common cause of death and disability around the world. Early diagnosis is critical for treatment and survival.
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A new strategy to rule-out and rule-in heart attacks in emergency departments will help physicians treat patients faster, found a clinical trial published in CMAJ (Canadian Medical Association Journal).

Acute myocardial infarction (MI) is a common cause of death and disability around the world. Early diagnosis is critical for treatment and survival.

Swiss and Spanish researchers conducted a clinical trial to determine whether a new technique, previously tested in a small pilot study, would be effective in determining whether a patient has had a heart attack. They enrolled 1320 patients who visited the emergency department with suspected acute MI and applied the high-sensitivity cardiac troponin T 1-hour algorithm to blood samples.

"Introducing the high-sensitivity cardiac troponin T 1-hour algorithm into clinical practice would represent a profound change and it is therefore important to determine if it works in a large patient group," states Dr. Tobias Reichlin, Division of Cardiology, University Hospital Basel, Switzerland.

With the algorithm, the researchers were able to determine that 786 (60%) of patients did not have an acute MI ("rule-out"), 216 (16%) were "rule-in" and 318 (24%) were to be observed because results were not conclusive.

"This rapid strategy incorporating high-sensitivity cardiac troponin T baseline values and absolute changes after the first hour substantially accelerates the management of patients with suspected acute MI by allowing safe rule-out as well as accurate rule-in of acute MI in 3 out of 4 patients," the authors conclude.


Story Source:

Materials provided by Canadian Medical Association Journal. Note: Content may be edited for style and length.


Journal Reference:

  1. Christian Mueller et al. Prospective validation of a 1-hour algorithm to rule-out and rule-in acute myocardial infarction using a high-sensitivity cardiac troponin T assay. CMAJ, April 2015 DOI: 10.1503/cmaj.141349

Cite This Page:

Canadian Medical Association Journal. "New strategy can help determine heart attack in patients within one hour." ScienceDaily. ScienceDaily, 13 April 2015. <www.sciencedaily.com/releases/2015/04/150413130607.htm>.
Canadian Medical Association Journal. (2015, April 13). New strategy can help determine heart attack in patients within one hour. ScienceDaily. Retrieved May 26, 2017 from www.sciencedaily.com/releases/2015/04/150413130607.htm
Canadian Medical Association Journal. "New strategy can help determine heart attack in patients within one hour." ScienceDaily. www.sciencedaily.com/releases/2015/04/150413130607.htm (accessed May 26, 2017).

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