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Men with learning difficulties four times more likely to die of testicular cancer

Date:
March 27, 2017
Source:
European Association of Urology
Summary:
People with learning difficulties are 4 times more likely to die of testicular cancer than the general population. This is the first work relating cancer deaths to learning difficulties, with researchers now testing if this finding applies to all cancers.
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People with learning difficulties are 4 times more likely to die of testicular cancer than the general population. This is the first work relating cancer deaths to learning difficulties, with researchers now testing if this finding applies to all cancers.

The UK study, which is presented at the European Association of Urology conference in London, has found that testicular cancer sufferers who also have learning disabilities (LD) have a 1 in 10 chance of dying from the cancer, as opposed to a 1 in 36 chance in the general population. As this is the first major study to look at cancer survival rates in people with learning difficulties, the authors don't yet know if this increased mortality rate applies to all cancers or just to testicular cancer.

Around one and a half million people in the UK are classified as having learning difficulties. Research has found that males with intellectual disabilities die on average 13 years earlier than the general population. In females the situation is even worse, women with intellectual difficulties die on average 20 years earlier. Most of these deaths are believed to be due to cardiovascular disease, but now a group of UK scientists and clinicians have looked at the testicular cancer incidence and how it relates to learning difficulties.

Using the NHS's Hospital Episode Statistics database, the team, based at the University of Birmingham identified 158,138 male patients with learning difficulties. Over a 14 year period from 2001 to 2015, they found that 331 had testicular cancer, and 32 died of cancer. In the general population 25,675 had testicular cancer with 713 cancer specific deaths, meaning that the rate of cancer deaths was significantly higher in people with learning difficulties.

The work's lead author Dr Mehran Afshar (St George's Hospital, London) said "We found that people with learning disabilities are not only more likely to develop testicular cancer, but are also far more likely to die from it than the general population. Testicular cancer is relatively rare, but if similar imbalances apply to all cancers, which we suspect to be the case, this would make excess cancer deaths associated with learning difficulties a significant public health issue. However, we don't yet have any statistics to confirm this. We are still processing the data on other cancers, such as prostate, breast and colorectal cancer."

"We propose that there might be several reasons which cause this disparity in survival, perhaps including the possibility that men with learning difficulties are not so good at self-examination, going to the doctor, and then following through with any treatment. It could also be that because consent is more difficult to obtain from these patients it affects the treatment they receive."

Although cure rates for testicular cancer are high, it is the 3rd leading cause of cancer death amongst men aged 18 to 50. Between 1979 and 2006 there was an 82% increase  in incidence in Europe (although rates have been stable since). Several high-profile cases have raised the public visibility of testicular cancer in the recent years, the cyclist Lance Armstrong being the best known. Overall, cancers are less common in patients with learning difficulties, although this is changing as LD patients are generally living longer.

Commenting, Professor Jens Sønksen (University of Copenhagen) of the EAU Scientific Congress Committee said; "Recently we have seen an increased focus on inequality in health care as it appears that people of different backgrounds receive health care of different quality.

This study is important because it identifies a vulnerable group of patients at increased risk of cancer mortality. As health care professionals we will need to develop methods to provide better health care focused specifically on people with intellectual disabilities."


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Materials provided by European Association of Urology. Note: Content may be edited for style and length.


Cite This Page:

European Association of Urology. "Men with learning difficulties four times more likely to die of testicular cancer." ScienceDaily. ScienceDaily, 27 March 2017. <www.sciencedaily.com/releases/2017/03/170327083448.htm>.
European Association of Urology. (2017, March 27). Men with learning difficulties four times more likely to die of testicular cancer. ScienceDaily. Retrieved May 23, 2017 from www.sciencedaily.com/releases/2017/03/170327083448.htm
European Association of Urology. "Men with learning difficulties four times more likely to die of testicular cancer." ScienceDaily. www.sciencedaily.com/releases/2017/03/170327083448.htm (accessed May 23, 2017).

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