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Silk clothing did not improve eczema in children

Date:
April 11, 2017
Source:
PLOS
Summary:
No significant differences were observed in eczema severity for children with moderate to severe eczema who wore silk garments compared with those who wore their usual clothing, according to a randomized controlled study.
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No significant differences were observed in eczema severity for children with moderate to severe eczema who wore silk garments compared with those who wore their usual clothing, according to a randomized controlled study published in PLOS Medicine by Kim Thomas from University of Nottingham, UK, and colleagues.

Clothing may play a role in either exacerbating or soothing eczema, and patients often avoid wool garments and turn to cotton and other fine weave fabrics, including silk. In the new study, 300 children age 1 to 15 years with moderate to severe eczema were recruited from five UK centers covering a range of rural and urban settings. The participants were randomly divided into two groups: half the children received the standard of care and the other half received the standard of care plus silk garments that are claimed to be beneficial for eczema.

After 6 months, there was no significant difference in eczema severity -- based on the Eczema Area and Severity Index -- and no difference in quality of life or medication use between the groups. The researchers report that the garments are unlikely to be cost-effective even if the small differences between groups were genuine, with a computed cost per quality adjusted life year of silk garments to be GBP 56,811.

A limitation of the study is that the use of an objective outcome measure (an eczema severity score assessed by research nurses) may underestimate changes in symptoms.

The authors say: "The results of this trial suggest that silk garments are unlikely to provide additional clinical or economic benefits over standard care for children with moderate to severe eczema."


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Journal Reference:

  1. Kim S. Thomas, Lucy E. Bradshaw, Tracey H. Sach, Jonathan M. Batchelor, Sandra Lawton, Eleanor F. Harrison, Rachel H. Haines, Amina Ahmed, Hywel C. Williams, Taraneh Dean, Nigel P. Burrows, Ian Pollock, Joanne Llewellyn, Clare Crang, Jane D. Grundy, Juliet Guiness, Andrew Gribbin, Eleanor J. Mitchell, Fiona Cowdell, Sara J Brown, Alan A. Montgomery. Silk garments plus standard care compared with standard care for treating eczema in children: A randomised, controlled, observer-blind, pragmatic trial (CLOTHES Trial). PLOS Medicine, 2017; 14 (4): e1002280 DOI: 10.1371/journal.pmed.1002280

Cite This Page:

PLOS. "Silk clothing did not improve eczema in children." ScienceDaily. ScienceDaily, 11 April 2017. <www.sciencedaily.com/releases/2017/04/170411151026.htm>.
PLOS. (2017, April 11). Silk clothing did not improve eczema in children. ScienceDaily. Retrieved May 28, 2017 from www.sciencedaily.com/releases/2017/04/170411151026.htm
PLOS. "Silk clothing did not improve eczema in children." ScienceDaily. www.sciencedaily.com/releases/2017/04/170411151026.htm (accessed May 28, 2017).

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