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Patients with Chagas disease are often infected with an intestinal parasite

A new study recommends implementing a combined screening programme for both infections among Latin American adults living in Europe

Date:
February 14, 2018
Source:
Barcelona Institute for Global Health (ISGlobal)
Summary:
In patients with Chagas disease, the odds of being infected by the intestinal worm Strongyloides stercoralis increases by two-fold, according to a new study. The study underlines the potential benefits of performing a combined screening for both infections among Latin American adults living in Europe.
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In patients with Chagas disease, the odds of being infected by the intestinal worm Strongyloides stercoralis increases by two-fold, according to a study led by the Barcelona Institute for Global Health (ISGlobal). The study, published in PLOS Neglected Tropical Diseases, underlines the potential benefits of performing a combined screening for both infections among Latin American adults living in Europe.

Chagas disease (caused by the parasite Trypanosoma cruzi) and strongyloidiasis (caused by the helminth S. stercoralis) are neglected tropical diseases that share a similar epidemiological burden and result in chronic infections with high morbidity and mortality.

In this retrospective study, the authors evaluated the association between Trypanosoma cruzi infection and strongyloidiasis in a cohort of Latin American migrants screened for both infections in the Hospital Clinic at Barcelona between January 2013 and April 2015. The results obtained with 361 individuals show that 14% of them were positive for strongyloidiasis and 49% were positive for T. cruzi. Factors associated with T. cruzi infection included being of Bolivian origin, coming from a a rural area and having lived in an adobe house. A higher percentage of patients with strongyloidiasis was infected by T. cruzi, and viceversa. The statistical analysis shows that T. cruzi infection was associated with a two-fold increase in the odds of strongyloidiasis in Latin American migrants attending a tropical diseases unit, even after adjusting for other epidemiological variables.

"Both diseases are strongly influenced by socioeconomic factors and poor healthcare systems," says Jose Muñoz, ISGlobal researcher and coordinator of the study.

"We have already demonstrated the cost-benefit of performing systemic Chagas screening in asymptomatic Latino American adults living in Europe," explains Joaquim Gascon. Given the high prevalence of strongyloidiasis in T. cruzi infected patients, the authors recommend implementing a combined screening program for both infections among Latin American adults living in Europe.


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Materials provided by Barcelona Institute for Global Health (ISGlobal). Note: Content may be edited for style and length.


Journal Reference:

  1. Pedro Puerta-Alcalde, Joan Gomez-Junyent, Ana Requena-Mendez, Maria Jesús Pinazo, Miriam José Álvarez-Martínez, Natalia Rodríguez, Joaquim Gascon, Jose Muñoz. High prevalence of S. Stercoralis infection among patients with Chagas disease: A retrospective case-control study. PLOS Neglected Tropical Diseases, 2018; 12 (1): e0006199 DOI: 10.1371/journal.pntd.0006199

Cite This Page:

Barcelona Institute for Global Health (ISGlobal). "Patients with Chagas disease are often infected with an intestinal parasite." ScienceDaily. ScienceDaily, 14 February 2018. <www.sciencedaily.com/releases/2018/02/180214111103.htm>.
Barcelona Institute for Global Health (ISGlobal). (2018, February 14). Patients with Chagas disease are often infected with an intestinal parasite. ScienceDaily. Retrieved March 18, 2024 from www.sciencedaily.com/releases/2018/02/180214111103.htm
Barcelona Institute for Global Health (ISGlobal). "Patients with Chagas disease are often infected with an intestinal parasite." ScienceDaily. www.sciencedaily.com/releases/2018/02/180214111103.htm (accessed March 18, 2024).

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