New! Sign up for our free email newsletter.
Reference Terms
from Wikipedia, the free encyclopedia

Personalized medicine

Currently, much of medical practice is based on "standards of care" that are determined by averaging responses across large cohorts. The theory has been that everyone should get the same care based on clinical trials.

Personalized Medicine is the concept that managing a patient's health should be based on the individual patient's specific characteristics, including age, gender, height/weight, diet, environment, etc.

Potential applications of personalized medicine

Personalized medicine aims to identify individuals at risk for common diseases such as cancer, heart disease, and diabetes. The simple family history has long been used by physicians to identify individuals at increased risk and to advise preventive measures such as lifestyle modifications (changes in diet, cessation of toxic habits, increased exercise) earlier screening, or even prophylactic medications or surgery.

Scientific advancements offer the potential to define an individual's risk based on their genetic make-up. Fields of Translational Research termed "-omics" (genomics, proteomics, and metabolomics) study the contribution of genes, proteins, and metabolic pathways to human physiology and variations of these pathways that can lead to disease susceptibility. It is hoped that these fields will enable new approaches to diagnosis, drug development, and individualized therapy.

Pharmacogenetics

Pharmacogenetics (also termed pharmacogenomics) is the field of study that examines the impact of genetic variation on the response to medications. This approach is aimed at tailoring drug therapy at a dosage that is most appropriate for an individual patient, with the potential benefits of increasing the efficacy and safety of medications. Gene-centered research may also speed the development of novel therapeutics.

Related Stories
 


Health & Medicine News

November 21, 2025

Researchers discovered that the common amino acid arginine can block harmful Aβ aggregation and reduce its toxic effects in Alzheimer’s disease models. In flies and mice, oral arginine lowered plaque levels, reduced inflammation, and improved ...
Researchers discovered that chemotherapy can accidentally trigger a stress alarm in immune cells, causing inflammation that damages nerves. Blocking this alarm protected mice from nerve pain and kept their nerves healthier. A drug already being ...
A new airflow device from UBC Okanagan engineers traps exhaled aerosols almost immediately, sharply reducing pathogen exposure in indoor spaces. Early simulations suggest it could outperform existing ventilation systems by a wide ...
Tiny ingestible spheres filled with engineered bacteria can detect intestinal bleeding by glowing when they encounter heme. Early tests in mice suggest they could become a quick, noninvasive way to monitor gut ...
A cutting-edge approach to immunotherapy shows that forcing cancer cells to die through necroptosis can dramatically boost the body's anti-tumor defenses. By combining three existing drugs, scientists reprogrammed malignant B cells so they release ...
Researchers found that hot tubs raise core body temperature more effectively than traditional or infrared saunas, leading to stronger boosts in blood flow and immune activity. Only hot-water ...
Researchers created a dissolvable microneedle patch that delivers IL-4 directly to damaged heart tissue, jump-starting repair after a heart attack. The targeted approach shifts immune cells into a healing mode while improving communication between ...
Researchers uncovered a powerful weakness in lung cancer by shutting down a protein that helps tumors survive stress. When this protein, FSP1, was blocked, lung tumors in mice shrank dramatically, with many cancer cells essentially triggering their ...
Researchers have recreated a miniature human bone marrow system that mirrors the real structure found inside our bones. The model includes the full mix of cells and signals needed for blood production and even maintains this process for weeks. It ...
A nationwide analysis has uncovered how sprawling fossil fuel infrastructure sits surprisingly close to millions of American homes. The research shows that 46.6 million people live within about a mile of wells, refineries, pipelines, storage sites, ...
Researchers discovered a way to keep T cells from wearing out during the fight against cancer, and the approach could make immune-based treatments far more powerful. They found that tumors use a particular molecular signal to weaken T cells, and ...
Scientists have developed a new molecule that breaks down beta-amyloid plaques by binding to excess copper in the brain. The treatment restored memory and reduced inflammation in rats, while also proving non-toxic and able to cross the blood–brain ...

Latest Headlines

updated 12:56 pm ET