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Reference Terms
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Personalized medicine

Currently, much of medical practice is based on "standards of care" that are determined by averaging responses across large cohorts. The theory has been that everyone should get the same care based on clinical trials.

Personalized Medicine is the concept that managing a patient's health should be based on the individual patient's specific characteristics, including age, gender, height/weight, diet, environment, etc.

Potential applications of personalized medicine

Personalized medicine aims to identify individuals at risk for common diseases such as cancer, heart disease, and diabetes. The simple family history has long been used by physicians to identify individuals at increased risk and to advise preventive measures such as lifestyle modifications (changes in diet, cessation of toxic habits, increased exercise) earlier screening, or even prophylactic medications or surgery.

Scientific advancements offer the potential to define an individual's risk based on their genetic make-up. Fields of Translational Research termed "-omics" (genomics, proteomics, and metabolomics) study the contribution of genes, proteins, and metabolic pathways to human physiology and variations of these pathways that can lead to disease susceptibility. It is hoped that these fields will enable new approaches to diagnosis, drug development, and individualized therapy.

Pharmacogenetics

Pharmacogenetics (also termed pharmacogenomics) is the field of study that examines the impact of genetic variation on the response to medications. This approach is aimed at tailoring drug therapy at a dosage that is most appropriate for an individual patient, with the potential benefits of increasing the efficacy and safety of medications. Gene-centered research may also speed the development of novel therapeutics.

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Health & Medicine News

August 1, 2026

A daily avocado may help lower heart disease risk in adults with obesity by reducing the number of LDL particles circulating in the blood. After six months, participants who ate an avocado each day experienced a decline associated with an estimated ...
Scientists have identified an immune response that may explain why statins cause muscle pain, weakness, and exercise intolerance in some people. The finding could eventually lead to treatments that protect muscles while preserving the drugs’ ...
Blood cancers that eventually worsen may carry detectable genetic warning signs years before patients develop serious symptoms. The findings could lead to earlier intervention while also helping doctors distinguish true cancer from harmless ...
A gene involved in the brain’s overnight cleaning system may change how strongly poor sleep affects Alzheimer’s-related brain changes. The findings point toward more personalized prevention strategies based on both genetics and sleep ...
New research challenges the decades-old idea that children experience an “adiposity rebound” when their BMI begins rising around age 6. Although BMI returns to earlier levels, a more reliable measure showed that body fat does not rebound at all. ...
A person’s sleeping brain may reveal warning signs of dementia long before memory problems begin. Researchers used machine learning to analyze EEG recordings from about 7,000 adults and found that an older-than-expected “brain age” was tied to ...
Researchers have uncovered a possible biological pathway connecting obesity to Alzheimer’s disease. Obesity appears to raise levels of certain fat molecules that can travel to the brain, disrupt its immune defenses, and promote harmful amyloid ...
Keeping a regular daily schedule may help reduce pain and depression, especially among older adults with insomnia. Researchers found that consistent times for waking, eating, socializing, and sleeping were linked to better well-being regardless of ...
A compound in rice bran may help calm an overactive gut by reducing the calcium signals that cause intestinal muscles to contract. Ferulic acid suppressed contractions triggered by several chemical messengers in laboratory experiments. The discovery ...
Taking a daily multivitamin may help older adults preserve the strength and stamina needed for everyday activities. After three years, users reported better functional health than those taking a placebo, although the preliminary findings still ...
A liquid brushed onto cavities in seconds may spare many young children from pain, infection, and surgery. A major U.S. trial found that silver diamine fluoride stopped decay in more than half of treated baby teeth. The treatment requires no ...
A new cooking method could make French fries crispier in less time while significantly limiting how much oil they absorb. Researchers propose combining microwave heating, which keeps oil out, with conventional frying, which provides the crunch ...

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