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Reference Terms
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Personalized medicine

Currently, much of medical practice is based on "standards of care" that are determined by averaging responses across large cohorts. The theory has been that everyone should get the same care based on clinical trials.

Personalized Medicine is the concept that managing a patient's health should be based on the individual patient's specific characteristics, including age, gender, height/weight, diet, environment, etc.

Potential applications of personalized medicine

Personalized medicine aims to identify individuals at risk for common diseases such as cancer, heart disease, and diabetes. The simple family history has long been used by physicians to identify individuals at increased risk and to advise preventive measures such as lifestyle modifications (changes in diet, cessation of toxic habits, increased exercise) earlier screening, or even prophylactic medications or surgery.

Scientific advancements offer the potential to define an individual's risk based on their genetic make-up. Fields of Translational Research termed "-omics" (genomics, proteomics, and metabolomics) study the contribution of genes, proteins, and metabolic pathways to human physiology and variations of these pathways that can lead to disease susceptibility. It is hoped that these fields will enable new approaches to diagnosis, drug development, and individualized therapy.

Pharmacogenetics

Pharmacogenetics (also termed pharmacogenomics) is the field of study that examines the impact of genetic variation on the response to medications. This approach is aimed at tailoring drug therapy at a dosage that is most appropriate for an individual patient, with the potential benefits of increasing the efficacy and safety of medications. Gene-centered research may also speed the development of novel therapeutics.

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June 21, 2026

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A newly identified molecule called OLE helped restore the brain’s immune cells to a more protective state in Alzheimer’s models. The treatment reduced toxic plaque buildup and improved memory, raising hopes for a new therapeutic ...
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Scientists at Mayo Clinic have uncovered a surprising new way the kidneys conserve water, revealing a hidden backup system that works independently of the hormone long believed to control the process. The discovery emerged when researchers testing ...
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A Rutgers study suggests GLP-1 drugs such as Ozempic and Wegovy may weaken the link between impulsive tendencies and violent behavior. The surprising finding hints that these medications could affect how people act on impulses, though researchers ...
Exposure to a common plastic chemical before and shortly after birth may have lasting effects on behavior. Researchers found that male rats exposed early in life to DEHP—a plasticizer used in products ranging from medical devices to toys—showed ...

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