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Computational neuroscience

Computational Neuroscience is an interdisciplinary science that links the diverse fields of neuroscience, computer science, physics and applied mathematics together. It serves as the primary theoretical method for investigating the function and mechanism of the nervous system. Computational neuroscience is distinct from psychological connectionism and theories of learning from disciplines such as machine learning, neural networks and statistical learning theory in that it emphasizes descriptions of functional and biologically realistic neurons and their physiology and dynamics. These models capture the essential features of the biological system at multiple spatial-temporal scales, from membrane currents, protein and chemical coupling to network oscillations and learning and memory. These computational models are used to test hypotheses that can be directly verified by current or future biological experiments.

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Mind & Brain News

January 1, 2026

A new study suggests the vagus nerve may be one of the heart’s most important defenders against aging. Researchers found that keeping this nerve connected to the heart helps protect heart cells and maintain strong pumping ability. Even partial ...
Scientists studying Alzheimer’s in African Americans have uncovered a striking genetic clue that may cut across racial lines. In brain tissue from more than 200 donors, the gene ADAMTS2 was significantly more active in people with Alzheimer’s ...
New research reveals a brighter side of ADHD, showing that adults who recognize and use their strengths feel happier, healthier, and less stressed. People with ADHD were more likely to identify traits like creativity, humor, and hyperfocus as ...
Cannabis products with higher THC levels may slightly reduce chronic pain, particularly nerve pain, according to a review of multiple clinical trials. The improvement was small and short-lived, while side effects were more common. Products with ...
ADHD stimulants appear to work less by sharpening focus and more by waking up the brain. Brain scans revealed that these medications activate reward and alertness systems, helping children stay interested in tasks they would normally avoid. The ...
Tiny lab-grown brains are offering an unprecedented look at how schizophrenia and bipolar disorder disrupt neural activity. Researchers found distinct electrical firing patterns that could identify ...
Weight loss restored healthy metabolism in both young and mid-aged mice, but the brain told a different story. In mid-aged animals, slimming down actually worsened inflammation in a brain region tied to appetite and energy balance. While this ...
A major new review has put hundreds of alternative autism treatments under the microscope—and most didn’t hold up. Scientists analyzed decades of research and found little reliable evidence that popular approaches like probiotics, acupuncture, ...
A new study suggests temporal lobe epilepsy may be linked to early aging of certain brain cells. When researchers removed these aging cells in mice, seizures dropped, memory improved, and some animals avoided epilepsy altogether. The treatment used ...
A new study suggests that dementia may be driven in part by faulty blood flow in the brain. Researchers found that losing a key lipid causes blood vessels to become overactive, disrupting circulation and starving brain tissue. When the missing ...
Alzheimer’s has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brain’s energy supply help drive the disease—and restoring that balance can reverse damage, even in ...
MIT scientists have achieved the first-ever lab synthesis of verticillin A, a complex fungal compound discovered in 1970. Its delicate structure stalled chemists for decades, despite differing from related molecules by only two atoms. With the ...

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