New! Sign up for our free email newsletter.
Reference Terms
from Wikipedia, the free encyclopedia

Psychoactive drug

A psychoactive drug or psychotropic substance is a chemical substance that acts primarily upon the central nervous system where it alters brain function, resulting in temporary changes in perception, mood, consciousness and behavior. These drugs may be used recreationally to purposefully alter one's consciousness (such as coffee, alcohol or cannabis), as entheogens for spiritual purposes (such as the mescaline-containing peyote cactus or psilocybin-containing mushrooms), and also as medication (such as the use of narcotics in controlling pain, stimulants to treat narcolepsy and attention disorders, as well as anti-depressants and anti-psychotics for treating neurological and psychiatric illnesses).

Many of these substances (especially the stimulants and depressants) can be habit-forming, causing chemical dependency and may lead to substance abuse. Conversely, others (namely the psychedelics) can, in certain circumstances, help to treat and even cure such addictions.

Related Stories
 


Health & Medicine News

January 29, 2026

An experimental drug once known for helping control type 2 diabetes may also fight heart disease. Researchers found IC7Fc lowered cholesterol, blood fats, and artery-clogging plaques while calming inflammation linked to heart attacks and strokes. ...
Scientists in Sweden and Norway have uncovered a promising way to spot Parkinson’s disease years—possibly decades—before its most damaging symptoms appear. By detecting subtle biological signals in the blood tied to how cells handle stress and ...
Scientists in South Korea have discovered that one of the most common malignant brain tumors in young adults may begin years before a tumor can be seen. IDH-mutant glioma, long treated by removing visible tumor tissue, actually starts when ...
Ozempic, Mounjaro, and Zepbound can drive impressive weight loss, but stopping them is often followed by rapid weight regain. Researchers found that people regain weight faster after quitting these ...
Helping care for grandchildren may offer an unexpected boost to brain health later in life. Researchers found that grandparents who provided childcare scored higher on memory and verbal skills than those who did not. The effect did not depend on how ...
Drinking heavily over many years is linked to a higher risk of colorectal cancer, especially rectal cancer, according to new research tracking U.S. adults for two decades. People who drank heavily throughout adulthood faced sharply higher risks than ...
Scientists at KAIST have found a way to turn a tumor’s own immune cells into powerful cancer fighters—right inside the body. Tumors are packed with macrophages, immune cells that should attack cancer but are usually silenced by the tumor ...
Researchers have developed smart nanoparticles that can seek out and destroy disease-causing proteins the body can’t normally eliminate. Unlike traditional drugs, these particles can reach ...
Cancer immunotherapy has been a game-changer, but many tumors still find ways to slip past the immune system. New research reveals a hidden trick: cancer cells can package the immune-blocking protein PD-L1 into tiny particles that circulate through ...
A massive international study of more than 3,100 long COVID patients uncovered a striking divide in how brain-related symptoms are reported around the world. In the U.S., the vast majority of non-hospitalized patients described brain fog, ...
Where your body stores fat may matter just as much as how much you carry—especially for your brain. Using advanced MRI scans and data from nearly 26,000 people, researchers identified two surprising fat patterns tied to faster brain aging, ...
Drinking tea, particularly green tea, is linked to better heart health, improved metabolism, and lower risks of chronic diseases like diabetes and cancer. It may also help protect the brain and preserve muscle strength as people age. However, ...

Latest Headlines

updated 12:56 pm ET