New! Sign up for our free email newsletter.
Reference Terms
from Wikipedia, the free encyclopedia

Psychoactive drug

A psychoactive drug or psychotropic substance is a chemical substance that acts primarily upon the central nervous system where it alters brain function, resulting in temporary changes in perception, mood, consciousness and behavior. These drugs may be used recreationally to purposefully alter one's consciousness (such as coffee, alcohol or cannabis), as entheogens for spiritual purposes (such as the mescaline-containing peyote cactus or psilocybin-containing mushrooms), and also as medication (such as the use of narcotics in controlling pain, stimulants to treat narcolepsy and attention disorders, as well as anti-depressants and anti-psychotics for treating neurological and psychiatric illnesses).

Many of these substances (especially the stimulants and depressants) can be habit-forming, causing chemical dependency and may lead to substance abuse. Conversely, others (namely the psychedelics) can, in certain circumstances, help to treat and even cure such addictions.

Related Stories
 


Health & Medicine News

October 22, 2025

Researchers at King’s College London have created the first evidence-based dietary guidelines for chronic constipation, finding real relief may come from kiwifruit, rye bread, and mineral water. Psyllium, probiotics, and magnesium oxide also ...
A wireless eye implant developed at Stanford Medicine has restored reading ability to people with advanced macular degeneration. The PRIMA chip works with smart glasses to replace lost photoreceptors using infrared light. Most trial participants ...
Scientists have uncovered a toxic alliance between Aβ and fibrinogen that may explain how Alzheimer’s disease begins. The two proteins together create stubborn clots that damage blood vessels and spark inflammation in the brain. These effects ...
A study found that daily vitamin D supplements helped slow telomere shortening—the cellular process linked to aging and disease. Researchers believe its anti-inflammatory effects may protect DNA. ...
New research reveals that exercise counteracts the mood-damaging effects of a Western-style diet through specific gut and hormonal mechanisms. Running restored metabolites tied to mental well-being and balanced key hormones like insulin and leptin. ...
A powerful new drug combination—niraparib added to standard prostate cancer therapy—has been shown to significantly delay disease progression in men with specific DNA repair gene mutations. In the large AMPLITUDE trial, patients receiving the ...
Mizzou scientists are exploring how a ketogenic diet may protect the brain and prevent Alzheimer’s in people genetically predisposed to it. Their study found that female mice with the APOE4 gene benefited most, showing improved gut and brain ...
Scientists from the University of Exeter has developed a precise method to interpret ankle blood pressure readings—an innovation that could transform care for people unable to have their arm blood pressure measured. By analyzing data from over ...
Menopause brings profound shifts not just in hormones but in the very structure of the brain. Scientists have found that gray matter in regions tied to memory and thinking can shrink, while white matter may show damage linked to blood flow issues. ...
Interval running condenses the powerful effects of regular running into shorter, high-intensity bursts. Research shows it can improve cardiovascular health, regulate blood sugar, and reduce body fat more effectively than longer steady runs. Just a ...
Researchers discovered that avian influenza (H5N1) can survive in raw milk cheese made from contaminated milk, even after the 60-day aging process required by the FDA. However, highly acidic cheeses like feta showed no signs of the virus, suggesting ...
Scientists at UCSF have uncovered evidence that multiple sclerosis silently damages the brain years before diagnosis. By studying proteins in blood samples, they identified early immune signals and markers of nerve damage. The findings point to IL-3 ...

Latest Headlines

updated 12:56 pm ET