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Reference Terms
from Wikipedia, the free encyclopedia

Tipping point

The phrase tipping point or angle of repose is a sociological term that refers to that dramatic moment when something unique becomes common. The concept has been applied in many fields from economics to epidemiology. It can also be compared to phase transition in physics or the propagation of memes or populations in an unbalanced ecosystem.

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Mind & Brain News

July 26, 2026

Scientists have identified a possible tipping point that helps determine whether Alzheimer’s-related brain changes lead to dementia. The key may lie in how the brain’s immune cells respond to plaques and tau, offering a promising new target for ...
The Backrooms began as a single eerie image of empty yellow rooms, but internet users transformed it into a vast fictional world that feels disturbingly real. Through videos, games, maps, survival ...
A decades-old diabetes drug just got a surprising twist. Scientists have discovered that metformin doesn’t just work in the liver and gut—it also acts directly in the brain, where it taps into a hidden control center for blood sugar. By ...
Even mild inflammation during pregnancy led mouse offspring to develop persistent brain overactivity, sensory sensitivity, repetitive behaviors, and increased seizure risk. Remarkably, one dose of rapamycin improved nearly all of these problems ...
Scientists expected SuperAgers might simply inherit fewer Alzheimer’s-related risks, but their genes looked much like those of typical older adults. Their extraordinary memories may instead come from still-unknown protective forces involving the ...
Newer oral drugs related to semaglutide medications such as Ozempic reduced pleasure-driven eating in mice by quieting a deep brain reward circuit. The finding could open new avenues for understanding food cravings and potentially treating substance ...
The longevity-linked APOE2 gene appears to protect brain cells by reducing DNA damage and helping neurons recover from stress. The finding could open a new path toward treatments that mimic APOE2’s defenses in people at higher genetic risk for ...
Miniature brain models grown from patients’ cells revealed striking differences in how Alzheimer’s-related tissue responds to an antidepressant. The organoids and the particles they release could eventually guide more personalized treatments and ...
A single dose of psilocybin produced measurable changes in brain activity and possible changes in brain structure that lasted for up to a month. Participants who experienced the greatest increase in flexible, varied brain activity also reported more ...
Watching television very often in midlife may be linked to troubling brain changes decades later. In a study of about 1,700 adults, frequent TV viewers later showed smaller brain regions involved in memory, decision-making, and visual processing, ...
Researchers have uncovered a surprising culprit behind sleep loss in Alzheimer’s disease: the brain’s own immune cells. In mice with amyloid plaques, overactive microglia triggered inflammation ...
A protein called SORLA may act as a powerful defense against the toxic tau tangles involved in Alzheimer’s disease. Mice with extra SORLA had less tau accumulation, less brain atrophy, and ...

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