Featured Research

from universities, journals, and other organizations

Common Genes Form New Family Tree For Animals

June 25, 1999
University Of Wisconsin-Madison
Looking deep within the genes of three very different kinds of animals, scientists have found enough molecular evidence to finally fell the animal kingdom's old family tree.

MADISON -- Looking deep within the genes of three very different kinds of animals, scientists have found enough molecular evidence to finally fell the animal kingdom's old family tree.

Related Articles

Writing this week in the British journal Nature, scientists from the University of Wisconsin-Madison, the University of Paris, Cambridge University and St. Petersburg University in Russia report the discovery of a common genetic theme that provides powerful new evidence to firmly place nearly all animals -- from mollusks to humans -- on a simplified, three-limbed tree of life.

For more than a hundred years, scientist have depended on morphology, the form and structure of animals, to determine their place on the family tree. But over the past few years, a new tree has been proposed based on comparisons of themes found in animal genes.

"In the last four or five years, this tree has been totally reorganized and if you're interested in evolutionary relationships, that's really important," said Sean B. Carroll, a professor of molecular biology at the Howard Hughes Medical Institute at the UW-Madison and a co-author of the report in Nature.

The new genetic evidence suggests that in the animal kingdom there are three primary lines of descent that first diverged from a common ancestor at least 540 million years ago, and that gave rise to most animals (with the exception of jellyfish and sponges) living today, said Jennifer K. Grenier, a Howard Hughes Medical Institute Fellow, UW-Madison graduate student and a lead author of the report.

The new study was based on exploration of so-called Hox genes in three distinct kinds of animals: an unsegmented marine worm related to insects, an unusual marine animal called a lamp shell, and a segmented worm related to earthworms and leeches. Hox genes comprise part of a toolbox that is central to animal development. They help organize cells into the different body parts and determine such things as number and placement of legs, wings and other appendages.

By looking for, and finding, essentially the same critical organizing genes in seemingly unrelated animals, the groups from Wisconsin, Paris and Cambridge could, in essence, look far back in time and infer what critical body-organizing genes were present in a common ancestor.

"The point is we're trying to find out the early history of animal evolution," said Carroll, and what we've found is that "the genetic toolbox was pretty sophisticated in the earliest animals. That toolbox has been called on and expressed in many different ways."

It's possible, Carroll explained, to infer the past existence of some genes by looking at fossils, which may reflect those genes in the anatomy of the fossil animal. It is also possible to determine what critical genes were at work hundreds of millions of years ago by analyzing the genes of the living descendants of animals found in the fossil record.

"When you actually look at the genes, the three-branched tree is supported," Carroll said.

All of the animals involved in the new study, although from widely divergent parts of the animal kingdom, have similar Hox genes, although with slight but significant variations, said Grenier. The upshot, she said, is that an ancient common ancestor conferred these genes on animals that subsequently evolved in dramatically different directions.

"Before these (modern) animals existed, these genes were around. There was a common ancestor 600 million years ago that had all these genes," Grenier said.

The new, three-limbed tree simplifies the previous animal kingdom family tree by substituting one branch in place of many offshoots first suggested through anatomical comparison.

"Similar (anatomical) traits don't necessarily reflect a closer relationship," Grenier explained. "We think there are fewer problems using molecular data" to map kinship among animals.

One intriguing upshot of the new study and others is that scientists, through genetic analysis, may learn something about the genes of an animal for which no fossil exists. Beyond 600 million years ago, the fossil record is skimpy at best, and scientists have no clue as to what the common ancestor of all animals actually looked like.

"There's no fossil. Five-hundred and forty million years ago is just about the end of the animal fossil record," said Grenier. "We don't know what (the common ancestor) looked like, but we think we know what its genes were."


NOTE TO PHOTO EDITORS: High-resolution images to accompany this story are available for downloading at: http://www.news.wisc.edu/newsphotos/animaltree.html

Story Source:

The above story is based on materials provided by University Of Wisconsin-Madison. Note: Materials may be edited for content and length.

Cite This Page:

University Of Wisconsin-Madison. "Common Genes Form New Family Tree For Animals." ScienceDaily. ScienceDaily, 25 June 1999. <www.sciencedaily.com/releases/1999/06/990625074421.htm>.
University Of Wisconsin-Madison. (1999, June 25). Common Genes Form New Family Tree For Animals. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/1999/06/990625074421.htm
University Of Wisconsin-Madison. "Common Genes Form New Family Tree For Animals." ScienceDaily. www.sciencedaily.com/releases/1999/06/990625074421.htm (accessed December 18, 2014).

Share This

More From ScienceDaily

More Plants & Animals News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations

Featured Videos

from AP, Reuters, AFP, and other news services

Navy Unveils Robot Fish

Navy Unveils Robot Fish

Reuters - Light News Video Online (Dec. 18, 2014) The U.S. Navy unveils an underwater device that mimics the movement of a fish. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
The Hottest Food Trends for 2015

The Hottest Food Trends for 2015

Buzz60 (Dec. 17, 2014) Urbanspoon predicts whicg food trends will dominate the culinary scene in 2015. Mara Montalbano (@maramontalbano) has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.


Breaking News:

Strange & Offbeat Stories

Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News


Free Subscriptions

Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile

Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?

Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins