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Disease-Causing Genetic Mutations In Sperm Increase With Men's Age

Date:
October 18, 2002
Source:
Johns Hopkins Medical Institutions
Summary:
Scientists from the McKusick-Nathans Institute for Genetic Medicine at Johns Hopkins may have discovered why a rare genetic disease is more common in children born to older fathers. The disease, Apert syndrome, leads to webbed fingers and early fusion of the skull bones and must be corrected by surgery.

Scientists from the McKusick-Nathans Institute for Genetic Medicine at Johns Hopkins may have discovered why a rare genetic disease is more common in children born to older fathers. The disease, Apert syndrome, leads to webbed fingers and early fusion of the skull bones and must be corrected by surgery. While Apert syndrome itself affects only 1 in 160,000 births, the scientists believe their findings could extend to many of the 20 or so other genetic conditions similarly linked to older fathers. The researchers are scheduled to present their findings Oct. 17 at the annual meeting of the American Society for Human Genetics in Baltimore.


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The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.


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Johns Hopkins Medical Institutions. "Disease-Causing Genetic Mutations In Sperm Increase With Men's Age." ScienceDaily. ScienceDaily, 18 October 2002. <www.sciencedaily.com/releases/2002/10/021018080014.htm>.
Johns Hopkins Medical Institutions. (2002, October 18). Disease-Causing Genetic Mutations In Sperm Increase With Men's Age. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2002/10/021018080014.htm
Johns Hopkins Medical Institutions. "Disease-Causing Genetic Mutations In Sperm Increase With Men's Age." ScienceDaily. www.sciencedaily.com/releases/2002/10/021018080014.htm (accessed April 20, 2014).

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