Featured Research

from universities, journals, and other organizations

Making A Safer Anthrax Vaccine Using Spinach

Date:
March 12, 2003
Source:
American Society For Microbiology
Summary:
Researchers at Thomas Jefferson University have developed a strategy for making a safer anthrax vaccine; enlisting the help of spinach plants to manufacture a key component.

BALTIMORE – March 10, 2003 – Researchers at Thomas Jefferson University have developed a strategy for making a safer anthrax vaccine; enlisting the help of spinach plants to manufacture a key component. They report their findings today at the American Society for Microbiology's Biodefense Research Meeting.

Related Articles


"Protective antigen (PA) of Bacillus anthracis is one of the three components of the anthrax toxin," says Alexander Karasev, a lead researcher on the study. "Purified PA is currently used as a vaccine against anthrax. However, the licensed vaccine derived from apathogenic B. anthracis has side effects and a more efficacious and safer vaccine is needed."

Karasev and his colleagues have genetically engineered a tobacco mosaic virus that, when inserted into spinach plants, instructs the plants to manufacture fragments of PA. The fragments can then easily be purified and used in a vaccine. They are already being used in the production of PA specific antibodies in laboratory animals.

"Plants can be an excellent vehicle for production of a subunit vaccine against anthrax based on protective antigen," says Karasev.

###

The American Society for Microbiology (ASM) is the largest single life science society, composed of over 42,000 scientists, teachers, physicians, and health professionals. Its mission is to promote research and training in the microbiological sciences and to assist communication between scientists, policymakers, and the public to improve health, economic well being, and the environment.

Further information on the ASM Biodefense Research Meeting can be found online at http://www.asmbiodefense.org .


Story Source:

The above story is based on materials provided by American Society For Microbiology. Note: Materials may be edited for content and length.


Cite This Page:

American Society For Microbiology. "Making A Safer Anthrax Vaccine Using Spinach." ScienceDaily. ScienceDaily, 12 March 2003. <www.sciencedaily.com/releases/2003/03/030312072233.htm>.
American Society For Microbiology. (2003, March 12). Making A Safer Anthrax Vaccine Using Spinach. ScienceDaily. Retrieved January 25, 2015 from www.sciencedaily.com/releases/2003/03/030312072233.htm
American Society For Microbiology. "Making A Safer Anthrax Vaccine Using Spinach." ScienceDaily. www.sciencedaily.com/releases/2003/03/030312072233.htm (accessed January 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, January 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
This Is What It's Like To Date A Med Student

This Is What It's Like To Date A Med Student

BuzzFeed (Jan. 23, 2015) Dating is now speed-dating... or studying. Video provided by BuzzFeed
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins