Featured Research

from universities, journals, and other organizations

Making A Safer Anthrax Vaccine Using Spinach

Date:
March 12, 2003
Source:
American Society For Microbiology
Summary:
Researchers at Thomas Jefferson University have developed a strategy for making a safer anthrax vaccine; enlisting the help of spinach plants to manufacture a key component.

BALTIMORE – March 10, 2003 – Researchers at Thomas Jefferson University have developed a strategy for making a safer anthrax vaccine; enlisting the help of spinach plants to manufacture a key component. They report their findings today at the American Society for Microbiology's Biodefense Research Meeting.

"Protective antigen (PA) of Bacillus anthracis is one of the three components of the anthrax toxin," says Alexander Karasev, a lead researcher on the study. "Purified PA is currently used as a vaccine against anthrax. However, the licensed vaccine derived from apathogenic B. anthracis has side effects and a more efficacious and safer vaccine is needed."

Karasev and his colleagues have genetically engineered a tobacco mosaic virus that, when inserted into spinach plants, instructs the plants to manufacture fragments of PA. The fragments can then easily be purified and used in a vaccine. They are already being used in the production of PA specific antibodies in laboratory animals.

"Plants can be an excellent vehicle for production of a subunit vaccine against anthrax based on protective antigen," says Karasev.

###

The American Society for Microbiology (ASM) is the largest single life science society, composed of over 42,000 scientists, teachers, physicians, and health professionals. Its mission is to promote research and training in the microbiological sciences and to assist communication between scientists, policymakers, and the public to improve health, economic well being, and the environment.

Further information on the ASM Biodefense Research Meeting can be found online at http://www.asmbiodefense.org .


Story Source:

The above story is based on materials provided by American Society For Microbiology. Note: Materials may be edited for content and length.


Cite This Page:

American Society For Microbiology. "Making A Safer Anthrax Vaccine Using Spinach." ScienceDaily. ScienceDaily, 12 March 2003. <www.sciencedaily.com/releases/2003/03/030312072233.htm>.
American Society For Microbiology. (2003, March 12). Making A Safer Anthrax Vaccine Using Spinach. ScienceDaily. Retrieved September 21, 2014 from www.sciencedaily.com/releases/2003/03/030312072233.htm
American Society For Microbiology. "Making A Safer Anthrax Vaccine Using Spinach." ScienceDaily. www.sciencedaily.com/releases/2003/03/030312072233.htm (accessed September 21, 2014).

Share This



More Health & Medicine News

Sunday, September 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins