Featured Research

from universities, journals, and other organizations

Fatty Foods Fight Inflammation

Date:
October 12, 2005
Source:
Journal of Experimental Medicine
Summary:
"Take two cheeseburgers and call me in the morning," may sound like far-fetched medical advice. After all, high fat foods can worsen blockages in blood vessels. But a new study in the October 17 issue of The Journal of Experimental Medicine shows that high fat foods can, at least in the gut, soothe inflammation. This action may stop immune cells from attacking food as a foreign invader.

"Take two cheeseburgers and call me in the morning," may sound likefar-fetched medical advice. After all, high fat foods can worsenblockages in blood vessels. But a new study in the October 17 issue ofThe Journal of Experimental Medicine shows that high fat foods can, atleast in the gut, soothe inflammation. This action may stop immunecells from attacking food as a foreign invader.

Eating -- particularly eating fat-rich foods -- causes cells in thesmall intestine to produce a hormone called cholecystokinin, or CCK.CCK stimulates digestion and gut peristalsis (the motion that propelsfood along the digestive tract), and also triggers satiation -- thefull feeling that prompts you to stop eating.

The study by Luyer and colleagues shows that fat-induced CCK can alsodampen inflammation in the gut, as rats fed a high-fat diet wereprotected against lethal bacteria-induced shock whereas those fed alow-fat diet were not. CCK sent signals to the brain through the vagusnerve, the nerve that provides the electrical regulation for manyinternal organs, including the gut and the heart. In response to CCK,vagus nerve endings in the gut released a neurotransmitter calledacetylcholine. Acetylcholine then bound to proteins on immune cells andturned the cells off.

The authors think this pathway might explain why the immune systemdoesn't react to food proteins and normal gut bacteria as if they wereforeign invaders. They also suggest that triggering this fat-drivenchain of events in patients might provide a way to reduce inflammatorycomplications after surgery.


Story Source:

The above story is based on materials provided by Journal of Experimental Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Journal of Experimental Medicine. "Fatty Foods Fight Inflammation." ScienceDaily. ScienceDaily, 12 October 2005. <www.sciencedaily.com/releases/2005/10/051011074219.htm>.
Journal of Experimental Medicine. (2005, October 12). Fatty Foods Fight Inflammation. ScienceDaily. Retrieved September 23, 2014 from www.sciencedaily.com/releases/2005/10/051011074219.htm
Journal of Experimental Medicine. "Fatty Foods Fight Inflammation." ScienceDaily. www.sciencedaily.com/releases/2005/10/051011074219.htm (accessed September 23, 2014).

Share This



More Health & Medicine News

Tuesday, September 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins