Featured Research

from universities, journals, and other organizations

Oregon Researchers Show How Resident Bacteria Shape Gut Development

Date:
June 26, 2006
Source:
University of Oregon
Summary:
University of Oregon researchers have shown that bacteria residing in the intestine shape gut development by means of several distinct signaling mechanisms. This research is now available in the online version of the journal Developmental Biology and will be published in the journal's August print edition.

University of Oregon researchers have shown that bacteria residing in the intestine shape gut development by means of several distinct signaling mechanisms.

This research is now available in the online version of the journal Developmental Biology and will be published in the journal's August print edition.

The researchers, led by Karen Guillemin, assistant professor of biology at the university's Institute of Molecular Biology, used "germ-free" zebrafish grown in sterile bubbles to examine how gut development differs in the absence of bacteria. They then added back individual bacterial strains or bacterial molecules to identify what signals were able to reverse different germ-free traits back to those of fish reared with normal gut bacteria. In one case, they found that a common component of the bacterial cell wall could restore normal levels of an intestinal enzyme whereas another trait, expression of a sugar on the intestinal cells, was regulated by specific members of the gut bacterial community.

"These findings demonstrate how germ-free zebrafish can be used to dissect the molecular dialogue between gut bacteria and their hosts," said Guillemin. "This is a dialogue which is important for the maturation of the gut during normal development and is likely to turn hostile in human conditions such as inflammatory bowel disease. A complete understanding of this dialogue could direct us toward better treatments for these diseases."


Story Source:

The above story is based on materials provided by University of Oregon. Note: Materials may be edited for content and length.


Cite This Page:

University of Oregon. "Oregon Researchers Show How Resident Bacteria Shape Gut Development." ScienceDaily. ScienceDaily, 26 June 2006. <www.sciencedaily.com/releases/2006/06/060626092302.htm>.
University of Oregon. (2006, June 26). Oregon Researchers Show How Resident Bacteria Shape Gut Development. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2006/06/060626092302.htm
University of Oregon. "Oregon Researchers Show How Resident Bacteria Shape Gut Development." ScienceDaily. www.sciencedaily.com/releases/2006/06/060626092302.htm (accessed April 18, 2014).

Share This



More Plants & Animals News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Vermont Goat Meat Gives Refugees Taste of Home

Vermont Goat Meat Gives Refugees Taste of Home

AP (Apr. 18, 2014) Dairy farmers and ethnic groups in Vermont are both benefiting from a unique collaborative effort that's feeding a growing need for fresh and affordable goat meat. (April 18) Video provided by AP
Powered by NewsLook.com
The Great British Farmland Boom

The Great British Farmland Boom

Reuters - Business Video Online (Apr. 17, 2014) Britain's troubled Co-operative Group is preparing to cash in on nearly 18,000 acres of farmland in one of the biggest UK land sales in decades. As Ivor Bennett reports, the market timing couldn't be better, with farmland prices soaring over 270 percent in the last 10 years. Video provided by Reuters
Powered by NewsLook.com
Flamingo Frenzy Ahead of Zoo Construction

Flamingo Frenzy Ahead of Zoo Construction

AP (Apr. 17, 2014) With plenty of honking, flapping, and fluttering, more than three dozen Caribbean flamingos at Zoo Miami were rounded up today as the iconic exhibit was closed for renovations. (April 17) Video provided by AP
Powered by NewsLook.com
Change of Diet Helps Crocodile Business

Change of Diet Helps Crocodile Business

Reuters - Business Video Online (Apr. 16, 2014) Crocodile farming has been a challenge in Zimbabwe in recent years do the economic collapse and the financial crisis. But as Ciara Sutton reports one of Europe's biggest suppliers of skins to the luxury market has come up with an unusual survival strategy - vegetarian food. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins