Featured Research

from universities, journals, and other organizations

Oregon Researchers Show How Resident Bacteria Shape Gut Development

Date:
June 26, 2006
Source:
University of Oregon
Summary:
University of Oregon researchers have shown that bacteria residing in the intestine shape gut development by means of several distinct signaling mechanisms. This research is now available in the online version of the journal Developmental Biology and will be published in the journal's August print edition.

University of Oregon researchers have shown that bacteria residing in the intestine shape gut development by means of several distinct signaling mechanisms.

This research is now available in the online version of the journal Developmental Biology and will be published in the journal's August print edition.

The researchers, led by Karen Guillemin, assistant professor of biology at the university's Institute of Molecular Biology, used "germ-free" zebrafish grown in sterile bubbles to examine how gut development differs in the absence of bacteria. They then added back individual bacterial strains or bacterial molecules to identify what signals were able to reverse different germ-free traits back to those of fish reared with normal gut bacteria. In one case, they found that a common component of the bacterial cell wall could restore normal levels of an intestinal enzyme whereas another trait, expression of a sugar on the intestinal cells, was regulated by specific members of the gut bacterial community.

"These findings demonstrate how germ-free zebrafish can be used to dissect the molecular dialogue between gut bacteria and their hosts," said Guillemin. "This is a dialogue which is important for the maturation of the gut during normal development and is likely to turn hostile in human conditions such as inflammatory bowel disease. A complete understanding of this dialogue could direct us toward better treatments for these diseases."


Story Source:

The above story is based on materials provided by University of Oregon. Note: Materials may be edited for content and length.


Cite This Page:

University of Oregon. "Oregon Researchers Show How Resident Bacteria Shape Gut Development." ScienceDaily. ScienceDaily, 26 June 2006. <www.sciencedaily.com/releases/2006/06/060626092302.htm>.
University of Oregon. (2006, June 26). Oregon Researchers Show How Resident Bacteria Shape Gut Development. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2006/06/060626092302.htm
University of Oregon. "Oregon Researchers Show How Resident Bacteria Shape Gut Development." ScienceDaily. www.sciencedaily.com/releases/2006/06/060626092302.htm (accessed September 17, 2014).

Share This



More Plants & Animals News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Some Tobacco Farmers Thrive Amid Challenges

Some Tobacco Farmers Thrive Amid Challenges

AP (Sep. 16, 2014) The South's tobacco country is surviving, and even thriving in some cases, as demand overseas keeps growers in the fields of one of America's oldest cash crops. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Scientists Given Rare Glimpse of 350-Kilo Colossal Squid

Scientists Given Rare Glimpse of 350-Kilo Colossal Squid

AFP (Sep. 16, 2014) Scientists say a female colossal squid weighing an estimated 350 kilograms (770 lbs) and thought to be only the second intact specimen ever found was carrying eggs when discovered in the Antarctic. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com
Raw: Scientists Examine Colossal Squid

Raw: Scientists Examine Colossal Squid

AP (Sep. 16, 2014) Squid experts in New Zealand thawed and examined an unusual catch on Tuesday: a colossal squid. It was captured in Antarctica's remote Ross Sea in December last year and has been frozen for eight months. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

AFP (Sep. 16, 2014) Since the arrival of Ebola in Ivory Coast, Ivorians have been abandoning their pets, particularly monkeys, in the fear that they may transmit the virus. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

      Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins