Featured Research

from universities, journals, and other organizations

Traditional Chinese Medicine For Diabetes Has Scientific Backing

Date:
July 31, 2006
Source:
Garvan Institute of Medical Research
Summary:
Reports of a traditional Chinese medicine having beneficial effects for people suffering from type 2 diabetes now has some scientific evidence to back up the claims. A collaboration between Chinese, Korean and Australian scientists at Sydney's Garvan Institute, has revealed that the natural plant product berberine could be a valuable new treatment.

Reports of a traditional Chinese medicine having beneficial effects for people suffering from type 2 diabetes now has some scientific evidence to back up the claims. A collaboration between Chinese, Korean, and Australian scientists at Sydney's Garvan Institute, has revealed that the natural plant product berberine could be a valuable new treatment.

Related Articles


Berberine is found in the roots and bark of a number of plants used for medicinal purposes including wound healing and treatment of diarrhoea. It has also been documented in Chinese literature as having a glucose lowering effect when administered to people with diabetes; yet, until now, its mode of action was unknown.

Garvan scientist Dr Jiming Ye says: "Our studies in animal models of diabetes show that berberine acts in part by activating an enzyme in the muscle and liver that is involved in improving sensitivity of the tissue to insulin -- this in turn helps lower blood sugar levels. In addition, it seems berberine can help reduce body weight".

Current medicines for treating type 2 diabetes include metformin and the TZD group of drugs. However, a large number of patients cannot tolerate metformin and the TZDs can cause undesirable weight gain. Therefore, it is critical to develop new therapies to treat type 2 diabetes, which is a growing health problem.

"Berberine has been used for decades, if not centuries, with few reported side effects. Given the limitations of existing medicines we are excited to have evidence that berberine may be a helpful new treatment for type 2 diabetes; however, despite its widespread use in traditional medicine practices, it will still have to be evaluated properly following the defined clinical trials process", said Professor James, head of the Garvan's Diabetes & Obesity Research Program and co-author of the Diabetes paper.

The next step is to investigate how berberine activates the enzyme that mediates these 'insulin-sensitising' effects.

This study will be published in the August issue of 'Diabetes'. The title is: Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin resistant states. Yun S. Lee, Woo S. Kim,Kang H. Kim, Myung J. Yoon, Hye J. Cho, Yun Shen, Ji-Ming Ye, Chul H. Lee, Won K. Oh, Chul T. Kim, Cordula Hohnen-Behrens, Alison Gosby, Edward W. Kraegen, David E. James, and Jae B. Kim

Background

Berberine (or plant material containing berberine) has also been documented as having anti-microbial, antitumour and anti-inflammatory properties as an oral medicine.

Additional information from the University of California San Diego website: http://meded.ucsd.edu/isp/2003/thomas/herb_goldenseal.html

The combination herbal supplement of echinacea and goldenseal has emerged as one of the top five herbal supplements sold in the world-wide market with annual sales in the US close to $50 million. Despite its popularity, much of the peer reviewed literature available on goldenseal deals specifically with the plant alkaloid component berberine, and not the herbal supplement itself. The berberine component of goldenseal is not considered toxic at doses used in clinical situations.


Story Source:

The above story is based on materials provided by Garvan Institute of Medical Research. Note: Materials may be edited for content and length.


Cite This Page:

Garvan Institute of Medical Research. "Traditional Chinese Medicine For Diabetes Has Scientific Backing." ScienceDaily. ScienceDaily, 31 July 2006. <www.sciencedaily.com/releases/2006/07/060731113333.htm>.
Garvan Institute of Medical Research. (2006, July 31). Traditional Chinese Medicine For Diabetes Has Scientific Backing. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2006/07/060731113333.htm
Garvan Institute of Medical Research. "Traditional Chinese Medicine For Diabetes Has Scientific Backing." ScienceDaily. www.sciencedaily.com/releases/2006/07/060731113333.htm (accessed March 5, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, March 5, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Doctor in Your Pocket Is Getting Smarter

Doctor in Your Pocket Is Getting Smarter

Reuters - Business Video Online (Mar. 5, 2015) Mobile apps are turning smartphones into a personal doctors, with users able to measure heart rate, blood pressure and even blood sugar. But will it change our behaviour? Ivor Bennett reports from the Mobile World Congress in Barcelona. Video provided by Reuters
Powered by NewsLook.com
AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

Newsy (Mar. 5, 2015) AbbVie announced Wednesday it will buy cancer drugmaker Pharmacyclics in a $21 billion deal. Video provided by Newsy
Powered by NewsLook.com
Adults Only Get The Flu Twice A Decade, Researchers Say

Adults Only Get The Flu Twice A Decade, Researchers Say

Newsy (Mar. 4, 2015) Researchers found adults only get the flu about once every five years. Scientists analyzed how a person&apos;s immunity builds up over time as well. Video provided by Newsy
Powered by NewsLook.com
Obamacare's Strange New Supreme Court Case

Obamacare's Strange New Supreme Court Case

Newsy (Mar. 4, 2015) President Obama&apos;s healthcare law is facing its second Supreme Court challenge, and it hinges on a single sentence. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins