Featured Research

from universities, journals, and other organizations

Traditional Chinese Medicine For Diabetes Has Scientific Backing

Date:
July 31, 2006
Source:
Garvan Institute of Medical Research
Summary:
Reports of a traditional Chinese medicine having beneficial effects for people suffering from type 2 diabetes now has some scientific evidence to back up the claims. A collaboration between Chinese, Korean and Australian scientists at Sydney's Garvan Institute, has revealed that the natural plant product berberine could be a valuable new treatment.

Reports of a traditional Chinese medicine having beneficial effects for people suffering from type 2 diabetes now has some scientific evidence to back up the claims. A collaboration between Chinese, Korean, and Australian scientists at Sydney's Garvan Institute, has revealed that the natural plant product berberine could be a valuable new treatment.

Related Articles


Berberine is found in the roots and bark of a number of plants used for medicinal purposes including wound healing and treatment of diarrhoea. It has also been documented in Chinese literature as having a glucose lowering effect when administered to people with diabetes; yet, until now, its mode of action was unknown.

Garvan scientist Dr Jiming Ye says: "Our studies in animal models of diabetes show that berberine acts in part by activating an enzyme in the muscle and liver that is involved in improving sensitivity of the tissue to insulin -- this in turn helps lower blood sugar levels. In addition, it seems berberine can help reduce body weight".

Current medicines for treating type 2 diabetes include metformin and the TZD group of drugs. However, a large number of patients cannot tolerate metformin and the TZDs can cause undesirable weight gain. Therefore, it is critical to develop new therapies to treat type 2 diabetes, which is a growing health problem.

"Berberine has been used for decades, if not centuries, with few reported side effects. Given the limitations of existing medicines we are excited to have evidence that berberine may be a helpful new treatment for type 2 diabetes; however, despite its widespread use in traditional medicine practices, it will still have to be evaluated properly following the defined clinical trials process", said Professor James, head of the Garvan's Diabetes & Obesity Research Program and co-author of the Diabetes paper.

The next step is to investigate how berberine activates the enzyme that mediates these 'insulin-sensitising' effects.

This study will be published in the August issue of 'Diabetes'. The title is: Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin resistant states. Yun S. Lee, Woo S. Kim,Kang H. Kim, Myung J. Yoon, Hye J. Cho, Yun Shen, Ji-Ming Ye, Chul H. Lee, Won K. Oh, Chul T. Kim, Cordula Hohnen-Behrens, Alison Gosby, Edward W. Kraegen, David E. James, and Jae B. Kim

Background

Berberine (or plant material containing berberine) has also been documented as having anti-microbial, antitumour and anti-inflammatory properties as an oral medicine.

Additional information from the University of California San Diego website: http://meded.ucsd.edu/isp/2003/thomas/herb_goldenseal.html

The combination herbal supplement of echinacea and goldenseal has emerged as one of the top five herbal supplements sold in the world-wide market with annual sales in the US close to $50 million. Despite its popularity, much of the peer reviewed literature available on goldenseal deals specifically with the plant alkaloid component berberine, and not the herbal supplement itself. The berberine component of goldenseal is not considered toxic at doses used in clinical situations.


Story Source:

The above story is based on materials provided by Garvan Institute of Medical Research. Note: Materials may be edited for content and length.


Cite This Page:

Garvan Institute of Medical Research. "Traditional Chinese Medicine For Diabetes Has Scientific Backing." ScienceDaily. ScienceDaily, 31 July 2006. <www.sciencedaily.com/releases/2006/07/060731113333.htm>.
Garvan Institute of Medical Research. (2006, July 31). Traditional Chinese Medicine For Diabetes Has Scientific Backing. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2006/07/060731113333.htm
Garvan Institute of Medical Research. "Traditional Chinese Medicine For Diabetes Has Scientific Backing." ScienceDaily. www.sciencedaily.com/releases/2006/07/060731113333.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins