Featured Research

from universities, journals, and other organizations

Higher Red Meat Intake May Increase Risk For Certain Breast Cancers

Date:
November 14, 2006
Source:
JAMA and Archives Journals
Summary:
Eating more red meat may be associated with a higher risk for hormone receptor--positive breast cancers in premenopausal women, according to a report in the Nov. 13 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Eating more red meat may be associated with a higher risk for hormone receptor--positive breast cancers in premenopausal women, according to a report in the November 13 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Related Articles


"Breast tumors are often characterized by hormone (estrogen and progesterone) receptor status," the authors write as background information in the article, meaning that the cancer is classified by whether these hormones can bind to proteins on the surface of the tumor. "Although the incidence rates of hormone receptor--negative tumors have remained relatively constant, the incidence of hormone receptor--positive tumors has been increasing in the United States, especially among middle-aged women." The diets of American women may be linked to this increase, since some foods--including certain components of red meat--can contain hormones or hormone-like compounds that influence tumors through their hormone receptors.

Eunyoung Cho, Sc.D., Brigham and Women's Hospital and Harvard Medical School, Boston, and colleagues studied the association between red meat consumption and breast cancer in 90,659 women who were part of the Nurses' Health Study II, a large ongoing study of nurses who responded to an initial questionnaire in 1989. Dr. Cho and colleagues followed the women from 1991 (when they had an average age of 36) through 2003. The participants filled out food questionnaires in 1991, 1995 and 1999, on which they recorded how often they regularly consumed more than 130 different foods and beverages. Every two years, they reported whether or not they had developed breast cancer; reported cases were confirmed through hospital records and pathology reports. Only women who were premenopausal and had not previously had cancer were included in this analysis, and those who went through natural menopause or had their ovaries removed during the 12 years of the study were excluded after that date.

By the end of the study, 1,021 women had developed breast cancer, including 512 cases that were estrogen and progesterone receptor positive, 167 that were estrogen and progesterone receptor negative, 110 with mixed status and 232 with unknown status. The highest intake of red meat was not significantly associated with the risk for breast cancer overall or for hormone receptor--negative cancers, but was associated with an increased risk for hormone receptor--positive cancer. Women who ate more than one and one-half servings of red meat per day had almost double the risk of hormone receptor--positive breast cancer compared with those who ate three or fewer servings per week. The associations remained similar when the researchers calculated red meat intake in grams instead of servings, and also when they split the women into five groups based on how much red meat they ate.

"Several biological mechanisms may explain the positive association between red meat intake and hormone receptor--positive breast cancer risk," the authors write. Known cancer-causing compounds in cooked or processed red meat increase mammary tumors in animals and have been suspected of causing breast cancer in humans. In addition, cattle in the United States are treated with hormones to promote growth, which could also influence breast cancer risk. The type of iron available in red meat also may enhance tumor formation.

"Given that most of the risk factors for breast cancer are not easily modifiable, these findings have potential public health implications in preventing breast cancer and should be evaluated further," the authors conclude.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Cite This Page:

JAMA and Archives Journals. "Higher Red Meat Intake May Increase Risk For Certain Breast Cancers." ScienceDaily. ScienceDaily, 14 November 2006. <www.sciencedaily.com/releases/2006/11/061113180252.htm>.
JAMA and Archives Journals. (2006, November 14). Higher Red Meat Intake May Increase Risk For Certain Breast Cancers. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2006/11/061113180252.htm
JAMA and Archives Journals. "Higher Red Meat Intake May Increase Risk For Certain Breast Cancers." ScienceDaily. www.sciencedaily.com/releases/2006/11/061113180252.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rural India's Low-Cost Sanitary Pad Revolution

Rural India's Low-Cost Sanitary Pad Revolution

AFP (Nov. 28, 2014) — One man hopes his invention -– a machine that produces cheap sanitary pads –- will help empower Indian women. Duration: 01:51 Video provided by AFP
Powered by NewsLook.com
Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) — In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
WHO Says Male Ebola Survivors Should Abstain From Sex

WHO Says Male Ebola Survivors Should Abstain From Sex

Newsy (Nov. 28, 2014) — WHO cites four studies that say Ebola can still be detected in semen up to 82 days after the onset of symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins