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BookmarkScienceDaily (Feb. 26, 2007) — Seafood allergy sufferers may soon be able to eat prawns without the fear of an adverse reaction. Chinese scientists have taken a promising step towards removing from prawns the proteins that cause an allergic response without resorting to genetic manipulation, reports Lisa Richards in Chemistry & Industry (http://www.chemind.org), the magazine of the SCI.
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Li Zhenxing led the research at the Ocean University of China. The team revealed that treating prawns with a combination of heat and irradiation significantly reduced the level of reactive proteins called allergens. They took blood from patients with shrimp allergies, added samples of treated and untreated prawn, and measured how antibodies in the blood reacted. They found that levels of 'Pen a 1', one of the major allergens, decreased 20-fold after treatment (Journal of the Science of Food and Agriculture DOI 10.1002/jsfa.2746).
Zhenxing's team suggests that irradiation damages the proteins, revealing hidden reactive amino acid residues. Subsequent heating then destroys the exposed residues. "Radiation and heat seems to be a promising method for reducing the immunoreactivity" say the researchers.
Samuel Lehrer of Tulane University in New Orleans, USA, is already working on removing allergens from prawns using genetic techniques. But Zhenxing's method could be preferable for people wary of eating genetically modified foods.
