Featured Research

from universities, journals, and other organizations

Race Affects Tobacco Absorption In Children, Study Suggests

Date:
March 13, 2007
Source:
American College of Chest Physicians
Summary:
New research suggests that a child’s race may be a factor in determining his/her susceptibility to tobacco toxins associated with environmental tobacco smoke (ETS). The study, published in the March issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), reveals that African American children with asthma, who are exposed to ETS, have significantly higher toxin levels when compared to their Caucasian counterparts.

New research suggests that a child’s race may be a factor in determining his/her susceptibility to tobacco toxins associated with environmental tobacco smoke (ETS). The study, published in the March issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), reveals that African American children with asthma, who are exposed to ETS, have significantly higher toxin levels when compared to their Caucasian counterparts.

“African American children suffer from higher rates of tobacco-related disorders, such as asthma, sudden-infant death syndrome, and low birth weight, and we need to know why,” said lead author Stephen Wilson MD, University of Cincinnati. “So our goal is to understand how certain populations—particularly those groups who are most susceptible—respond to ETS exposure.”

Dr. Wilson and colleagues from the Cincinnati Children’s Hospital Medical Center examined 220 tobacco-exposed children with asthma, who had previously participated in the Cincinnati Asthma Prevention study. Researchers studied a bi-racial, community-based sample (55% African American) of children ranging in ages 5 to 12. All of the children had physician-diagnosed asthma, symptoms consistent with persistent asthma, and were exposed to at least five cigarettes per day in or around the home.

Researchers tested for levels of cotinine, a nicotine metabolite, by collecting serum and hair samples at baseline, 6 months, and 1 year. Serum samples accounted for short-term tobacco exposure and hair samples accounted for long-term tobacco exposure.

“Cotinine is a product of nicotine metabolism. When people inhale or ingest nicotine, the body uses proteins to convert it into cotinine,” said Dr. Wilson, “and, currently, measuring cotinine in various biologic specimens is a widely used method for assessing nonsmokers’ exposure to ETS.”

Researchers also avoided reporting parental bias by actively measuring levels of tobacco smoke in the home. Each study participant had a nicotine dosimeter placed in his or her home at baseline and at the 6-month visit. These dosimeters were removed at the 6-month and 1-year visits, and were used to objectively measure each child’s level of ETS exposure.

No racial differences were reported in levels of ETS exposure outside of the home or in air nicotine levels at the 6-month or 1-year study visits. But, results indicated that while African-American children spent less time exposed to ETS, they showed significantly higher levels of cotinine compared to Caucasian children. On average, serum cotinine levels in the African-American participants were 32 percent higher than in the Caucasian participants, and hair cotinine levels were 4 times that of the Caucasian participants.

“Previous studies of adult smokers, as well as cross-sectional studies of nonsmokers have demonstrated similar racial differences in serum cotinine, however, we were surprised at the magnitude of the racial differences in the hair continine,” said Dr. Wilson. “African-American children may “handle” environmental tobacco smoke differently than white children, so these results raise questions as to whether there are racial differences in other tobacco toxicants, as well.”

“Exposure to tobacco smoke is dangerous for everyone, regardless of age or race,” said Mark J. Rosen, MD, FCCP, President of the American College of Chest Physicians. “These findings underline the importance of eliminating environmental tobacco smoke in every setting, especially those where children are present.”

CHEST is a peer-reviewed journal published by the ACCP. It is available online each month at http://www.chestjournal.org. The journal’s website also provides public access to thousands of archived studies, dating back to 1946—a newly added feature that is free of charge. The ACCP represents 16,600 members who provide clinical respiratory care, sleep medicine, critical care, and cardiothoracic patient care in the United States and throughout the world. The ACCP’s mission is to promote the prevention and treatment of diseases of the chest through leadership, education, research, and communication. For more information about the ACCP, please visit the ACCP Web site at http://www.chestnet.org.


Story Source:

The above story is based on materials provided by American College of Chest Physicians. Note: Materials may be edited for content and length.


Cite This Page:

American College of Chest Physicians. "Race Affects Tobacco Absorption In Children, Study Suggests." ScienceDaily. ScienceDaily, 13 March 2007. <www.sciencedaily.com/releases/2007/03/070312231855.htm>.
American College of Chest Physicians. (2007, March 13). Race Affects Tobacco Absorption In Children, Study Suggests. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2007/03/070312231855.htm
American College of Chest Physicians. "Race Affects Tobacco Absorption In Children, Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2007/03/070312231855.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Microneedle Patch Promises Painless Pricks

Microneedle Patch Promises Painless Pricks

Reuters - Innovations Video Online (Oct. 18, 2014) Researchers at The National University of Singapore have invented a new microneedle patch that could offer a faster and less painful delivery of drugs such as insulin and painkillers. Video provided by Reuters
Powered by NewsLook.com
Raw: Nurse Nina Pham Arrives in Maryland

Raw: Nurse Nina Pham Arrives in Maryland

AP (Oct. 17, 2014) The first nurse to be diagnosed with Ebola at a Dallas hospital walked down the stairs of an executive jet into an ambulance at an airport in Frederick, Maryland, on Thursday. Pham will be treated at the National Institutes of Health. (Oct. 16) Video provided by AP
Powered by NewsLook.com
Raw: Cruise Ship Returns to US Over Ebola Fears

Raw: Cruise Ship Returns to US Over Ebola Fears

AP (Oct. 17, 2014) A Caribbean cruise ship carrying a Dallas health care worker who is being monitored for signs of the Ebola virus is heading back to Texas, US, after being refused permission to dock in Cozumel, Mexico. (Oct. 17) Video provided by AP
Powered by NewsLook.com
Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

AFP (Oct. 17, 2014) All four suspected Ebola cases admitted to hospitals in Spain on Thursday have tested negative for the deadly virus in a first round of tests, the government said Friday. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins