Featured Research

from universities, journals, and other organizations

Second Extremely Resistant Bacteria Sequenced Is Surprisingly Different From First

Date:
September 28, 2007
Source:
Public Library of Science
Summary:
Researchers have completed the whole-genome sequence of Deinococcus geothermalis, which is only the second extremely radiation- and desiccation-resistant bacterium to be sequenced. The first was for the Guinness World Records-holder Deinococcus radiodurans, which for 50 years has been the subject of extensive investigations aimed at solving the mystery of how this microbe and its close relatives survive immense doses of x-rays and gamma-rays. Most surprisingly, many of the unique D. radiodurans genes that were strongly implicated in resistance over the last decade have turned out to be unrelated to its survival, and are not present in D. geothermalis.

Researchers have completed the whole-genome sequence of Deinococcus geothermalis, which is only the second extremely radiation- and desiccation-resistant bacterium to be sequenced.

Related Articles


The first was for the Guinness World Records-holder Deinococcus radiodurans, which for 50 years has been the subject of extensive investigations aimed at solving the mystery of how this microbe and its close relatives survive immense doses of x-rays and gamma-rays.

Most surprisingly, many of the unique D. radiodurans genes that were strongly implicated in resistance over the last decade have turned out to be unrelated to its survival, and are not present in D. geothermalis.

Using computer-based systems to compare the D. geothermalis genome sequence with the sequence of D. radiodurans, a minimal set of genes which encode extreme resistance was defined. Far fewer genes than initially believed appear to be responsible for the extreme resistance trait, which bodes well for the long-term prospects of conferring radiation resistance to other organisms.

The phenomenal resistance of Deinococcus bacteria has given rise to numerous descriptions of their origin, including that they evolved on Mars under harsh cosmic radiation. The present analysis firmly places the origin of Deinococcus bacteria on Earth, where the evolutionary steps that led to their survival mechanisms clearly occurred in their terrestrial ancestors - most likely in a desert near you.

Results of a recent study titled "Deinococcus geothermalis: The Pool of Extreme Radiation Resistance Genes Shrinks," will be published in the Sept. 26 edition of PLoS One.

The study was headed by Michael J. Daly, Ph.D., associate professor at the Uniformed Services University of the Health Sciences' (USU), Department of Pathology.

Deinococcus geothermalis was chosen for whole-genome sequencing by the U. S. Department of Energy (DOE), Office of Science, Office of Biological and Environmental Research with Dr. Daly as the Principal Investigator. The genome sequence was acquired at the DOE-Joint Genome Institute (JGI), Walnut Creek, CA, and subjected to comparative analysis at the National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health (NIH), Bethesda, Md. D. geothermalis was previously engineered by Daly's group for cleanup of radioactive waste sites. The three-year project was a collaboration between USU, DOE-JGI, NIH, DOE's Advanced Photon Source and Pacific Northwest National Laboratory, and the Russian Academy of Sciences.

Citation: Makarova KS, Omelchenko MV, Gaidamakova EK, Matrosova VY, Vasilenko A, et al (2007) Deinococcus geothermalis: The Pool of Extreme Radiation Resistance Genes Shrinks. PLoS ONE 2(9): e955. doi:10.1371/journal.pone.0000955


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Cite This Page:

Public Library of Science. "Second Extremely Resistant Bacteria Sequenced Is Surprisingly Different From First." ScienceDaily. ScienceDaily, 28 September 2007. <www.sciencedaily.com/releases/2007/09/070926191533.htm>.
Public Library of Science. (2007, September 28). Second Extremely Resistant Bacteria Sequenced Is Surprisingly Different From First. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2007/09/070926191533.htm
Public Library of Science. "Second Extremely Resistant Bacteria Sequenced Is Surprisingly Different From First." ScienceDaily. www.sciencedaily.com/releases/2007/09/070926191533.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
New Dinosaur Species Found in Museum Collection

New Dinosaur Species Found in Museum Collection

Reuters - Innovations Video Online (Nov. 27, 2014) A British palaeontologist has discovered a new species of dinosaur while studying fossils in a Canadian museum. Pentaceratops aquilonius was related to Triceratops and lived at the end of the Cretaceous Period, around 75 million years ago. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Tryptophan Isn't Making You Sleepy On Thanksgiving

Tryptophan Isn't Making You Sleepy On Thanksgiving

Newsy (Nov. 27, 2014) Tryptophan, a chemical found naturally in turkey meat, gets blamed for sleepiness after Thanksgiving meals. But science points to other culprits. Video provided by Newsy
Powered by NewsLook.com
Classic Hollywood Memorabilia Goes Under the Hammer

Classic Hollywood Memorabilia Goes Under the Hammer

Reuters - Entertainment Video Online (Nov. 26, 2014) The iconic piano from "Casablanca" and the Cowardly Lion suit from "The Wizard of Oz" fetch millions at auction. Sara Hemrajani reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins