Featured Research

from universities, journals, and other organizations

Three Genetic Prostate Cancer Risk Factors Identified

Date:
October 11, 2007
Source:
Journal of the National Cancer Institute
Summary:
Three separate locations on human chromosome 8q24 appear to be independently associated with an increased risk of prostate cancer. Evidence for genetic susceptibility to prostate cancer is quite strong. Several chromosome regions have been identified that may contain important prostate cancer-related genes.

Three separate locations on human chromosome 8q24 appear to be independently associated with an increased risk of prostate cancer.

Related Articles


Evidence for genetic susceptibility to prostate cancer is quite strong. Several chromosome regions have been identified that may contain important prostate cancer-related genes.

S. Lilly Zheng, M.D., of Wake Forest University School of Medicine in Winston-Salem, N.C., and colleagues at Johns Hopkins University School of Medicine examined 18 single-nucleotide polymorphisms on one such chromosome region. Three locations in that chromosome region were associated with an increased risk of prostate cancer among men of European American ancestry.

"Because the alleles associated with risk at these independent loci are common (i.e., at least one was present in more than one-third of the men in our study) and their effects are additive, our results indicate that 8q24 harbors factors that account for a substantial proportion of the genetic risk for this common disease," the authors write.

In an accompanying editorial, Sharon Savage, M.D., and Mark Greene, M.D., of the National Cancer Institute in Bethesda, Md., review other recently published genetic association studies involving this chromosome region and prostate cancer risk. They also discuss how more data sharing from genetic association studies has accelerated the pace of genomic research and discovery.

"The precedent set by the Human Genome Project and the advent of genome-wide association studies bring the need for innovative data-sharing policies to the forefront of the genetic association field," the editorialists write.

This research was published October 9 in the Journal of the National Cancer Institute.


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Journal of the National Cancer Institute. "Three Genetic Prostate Cancer Risk Factors Identified." ScienceDaily. ScienceDaily, 11 October 2007. <www.sciencedaily.com/releases/2007/10/071009164136.htm>.
Journal of the National Cancer Institute. (2007, October 11). Three Genetic Prostate Cancer Risk Factors Identified. ScienceDaily. Retrieved October 30, 2014 from www.sciencedaily.com/releases/2007/10/071009164136.htm
Journal of the National Cancer Institute. "Three Genetic Prostate Cancer Risk Factors Identified." ScienceDaily. www.sciencedaily.com/releases/2007/10/071009164136.htm (accessed October 30, 2014).

Share This



More Health & Medicine News

Thursday, October 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Mind-Controlled Prosthetic Arm Restores Amputee Dexterity

Reuters - Innovations Video Online (Oct. 29, 2014) A Swedish amputee who became the first person to ever receive a brain controlled prosthetic arm is able to manipulate and handle delicate objects with an unprecedented level of dexterity. The device is connected directly to his bone, nerves and muscles, giving him the ability to control it with his thoughts. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Google To Use Nanoparticles, Wearables To Detect Disease

Google To Use Nanoparticles, Wearables To Detect Disease

Newsy (Oct. 29, 2014) Google X wants to improve modern medicine with nanoparticles and a wearable device. It's all an attempt to tackle disease detection and prevention. Video provided by Newsy
Powered by NewsLook.com
Can Drinking Milk Lead To Early Death?

Can Drinking Milk Lead To Early Death?

Newsy (Oct. 29, 2014) Researchers in Sweden released a study showing heavy milk drinkers face an increased mortality risk from a variety of causes. Video provided by Newsy
Powered by NewsLook.com
Obama: The US Will Not 'run and Hide' From Ebola

Obama: The US Will Not 'run and Hide' From Ebola

AP (Oct. 29, 2014) Surrounded by health care workers in the White House East Room, President Barack Obama said the U.S. will likely see additional Ebola cases in the weeks ahead. But he said the nation can't seal itself off in the fight against the disease. (Oct. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins