Featured Research

from universities, journals, and other organizations

Cigarette Smoke May Enhance HPV And Increase Risk Of Cervical Cancer

Date:
January 23, 2008
Source:
American Society for Microbiology
Summary:
For the first time researchers suggest a direct interaction between cigarette smoke carcinogens and the human papillomavirus that may lead to increased risk of cervical cancer.

New research suggests a direct interaction between cigarette smoke carcinogens and the human papillomavirus that may lead to increased risk of cervical cancer.
Credit: iStockphoto

For the first time researchers from Pennsylvania State University College of Medicine suggest a direct interaction between cigarette smoke carcinogens and the human papillomavirus that may lead to increased risk of cervical cancer. They report their findings in the January 2008 issue of the Journal of Virology.

Cervical cancer is the third leading cancer type in women worldwide. Over 90% of the cases presented have been linked to human papillomavirus (HPV). Many women unknowingly carry HPV and the virus naturally regresses on its own over time. HPV will only progress into cervical cancer in a small percentage of women, but past studies have proposed cigarette smoking to be a likely influence.

HPV types 16, 18, and 31 are the most commonly associated with cervical cancer. In the study researchers detected benzo[a]pyrene (BaP), a major carcinogen in cigarette smoke, in the cervical mucus and tested its interaction with HPV. Levels of HPV type 31 increased by 10-fold following exposure to high concentrations of the BaP carcinogen. Levels of HPV types 16 and 18 were also elevated after exposure to BaP.

“Overall, BaP modulation of the HPV life cycle could potentially enhance viral persistence, host tissue carcinogenesis, and permissiveness for cancer progression,” say the researchers.

Reference: S. Alam, M.J. Conway, H.S. Chen, C. Meyers. 2008. The cigarette smoke carcinogen benzo[a]pyrene enhances human papillomavirus synthesis. Journal of Virology, 82. 2: 1053-1058.


Story Source:

The above story is based on materials provided by American Society for Microbiology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Microbiology. "Cigarette Smoke May Enhance HPV And Increase Risk Of Cervical Cancer." ScienceDaily. ScienceDaily, 23 January 2008. <www.sciencedaily.com/releases/2008/01/080122102342.htm>.
American Society for Microbiology. (2008, January 23). Cigarette Smoke May Enhance HPV And Increase Risk Of Cervical Cancer. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2008/01/080122102342.htm
American Society for Microbiology. "Cigarette Smoke May Enhance HPV And Increase Risk Of Cervical Cancer." ScienceDaily. www.sciencedaily.com/releases/2008/01/080122102342.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins