Featured Research

from universities, journals, and other organizations

Scientists 'Paint' Viruses To Track Their Fate In The Body

Date:
May 21, 2008
Source:
Federation of American Societies for Experimental Biology
Summary:
Here's a new twist on the relationship between biology and art. Researchers describe how they were able to coat--or paint--viruses with proteins. This breakthrough should boost the efficiency of some forms of gene therapy, help track and treat viral disease and evolution, improve the efficiency of vaccines, and ultimately allow health-care professionals track the movement of viral infections within the body.

Biologists from Austria and Singapore developed a technique that adds a new twist on the relationship between biology and art. Researchers describe how they were able to coat--or paint--viruses with proteins. This breakthrough should give a much-needed boost to the efficiency of some forms of gene therapy, help track and treat viral disease and evolution, improve the efficiency of vaccines, and ultimately allow health care professionals track the movement of viral infections within the body. Specifically, the new method should make it easier to track and treat infectious diseases such as HIV/AIDS, influenza, hepatitis C, and dengue fever.

Related Articles


And because viruses can also be used to introduce biotechnology drugs and replacement genes, and act as vaccines, this research should lead to new treatments for cancer, cardiovascular, metabolic and inherited disorders.

"This technology should provide a new tool for the treatment of many diseases," said Brian Salmons, one of scientists who co-authored the study. "Even if you are working with a virus that is unknown or poorly characterized, it is still possible to modify or paint it. This is very interesting for emerging diseases."

In the article in the FASEB journal, Salmons and colleagues explain how they mixed purified proteins (glycosylphophatidylinositol anchor proteins) with lipid membranes to make it possible to bind these proteins to the outer "skin" (the lipid envelope) of viruses. Even with the new paint job, the viruses remained infectious. While the experiment only involved one type of protein and two types of viral vectors, Salmons says the technique could be expanded and used to apply "paint" made up of other proteins, dyes, and a variety of unique markers.

"Biology and art converge daily: people paint their nails, color their hair, and tattoo their skin," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "Now this convergence has entered a new dimension as painted viruses permit scientists to track, cure and prevent disease."


Story Source:

The above story is based on materials provided by Federation of American Societies for Experimental Biology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Association of glycosylphosphatidylinositol-anchored protein with retroviral particles. Christoph Metzner, Meike M Mostegl, Walter H. Günzburg, Brian Salmons, and John A. Dangerfield. FASEB. Published online before print May 13, 2008 as doi: 10.1096/fj.08-108217. [link]

Cite This Page:

Federation of American Societies for Experimental Biology. "Scientists 'Paint' Viruses To Track Their Fate In The Body." ScienceDaily. ScienceDaily, 21 May 2008. <www.sciencedaily.com/releases/2008/05/080520103432.htm>.
Federation of American Societies for Experimental Biology. (2008, May 21). Scientists 'Paint' Viruses To Track Their Fate In The Body. ScienceDaily. Retrieved October 26, 2014 from www.sciencedaily.com/releases/2008/05/080520103432.htm
Federation of American Societies for Experimental Biology. "Scientists 'Paint' Viruses To Track Their Fate In The Body." ScienceDaily. www.sciencedaily.com/releases/2008/05/080520103432.htm (accessed October 26, 2014).

Share This



More Health & Medicine News

Sunday, October 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
Toxin-Packed Stem Cells Used To Kill Cancer

Toxin-Packed Stem Cells Used To Kill Cancer

Newsy (Oct. 25, 2014) — A Harvard University Research Team created genetically engineered stem cells that are able to kill cancer cells, while leaving other cells unharmed. Video provided by Newsy
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins