Featured Research

from universities, journals, and other organizations

Compound That Helps Rice Grow Reduces Nerve, Vascular Damage From Diabetes

Date:
July 30, 2008
Source:
Medical College of Georgia
Summary:
Researchers have found that a compound that helps rice seed grow, springs back into action when brown rice is placed in water overnight before cooking, significantly reducing the nerve and vascular damage that often result from diabetes.

Researchers have found that a compound that helps rice seed grow, springs back into action when brown rice is placed in water overnight before cooking, significantly reducing the nerve and vascular damage that often result from diabetes.
Credit: Image courtesy of Medical College of Georgia

You may want to soak your brown rice.

Related Articles


Researchers have found that a compound that helps rice seed grow, springs back into action when brown rice is placed in water overnight before cooking, significantly reducing the nerve and vascular damage that often result from diabetes.

"You have to let it grow, germinate a little bit," says Dr. Robert K. Yu, director of the Institute of Molecular Medicine and Genetics and Institute of Neuroscience at the Medical College of Georgia. "Some of the active ingredients generated as a result of the germination process are beneficial to you."

Germinated brown rice's ability to help diabetics lower their blood sugar has been shown but how it works remained unknown. New research, published online in the Journal of Lipid Research, shows the growth factor acylated steryl glucosides or ASG, helps normalize blood sugar and enzymes that are out-of-whack in diabetes.

"The advantage of knowing this key ingredient and its structure is we can now make a ton of it; you don't have to rely on rice to produce it or eating rice to get this beneficial effect," says Dr. Yu, the paper's corresponding author.

Studies were done in animal models of type 1 diabetes with two different blood sugar levels that reflect patients' varying blood sugars. They were fed diets of white, brown or pre-germinated brown rice. Unlike white rice, less-processed brown rice still has some of the germ or growth structure that, after about 24 hours in water, resumes activity. Scientists watched as the resurrected ASG, a growth factor and lipid, helped normalize metabolism.

"When blood sugar levels increase, the metabolic balance changes," says Dr. Seigo Usuki, neurobiologist in the MCG School of Medicine and the paper's first author. "Part of the way we know this growth factor works is by increasing levels of good enzymes that are decreased in diabetes."

Dr. Usuki is talking about enzymes such as ATPase, which help maintain nerve membranes so they can conduct electricity and communicate. Decrease of ATPase is a hallmark of the nerve damage that accompanies diabetes. Also reduced in diabetes is homocysteine-thiolactonase, or HTase, an enzyme that decreases levels of homocysteine, a known risk factor for vascular disease. The liver produces a low level of homocysteine but that level is elevated in diabetes while the enzyme that controls it decreases.  Unchecked, homocysteine makes oxidative stress compounds that injure and kill cells. HTase is one way HDL, the so-called "good cholesterol," helps protect blood vessels from disease. A regular diet of pre-germinated brown rice diet helps get both back to a healthier level.

Fancl Hatsuga Genmai Co., Ltd., in Yokohama, Japan, which funded the studies and supplied the pre-germinated rice, already is working with Dr. Usuki on a supplement that can provide consumers who prefer not to soak – or eat – rice with the benefits of ASG.

The MCG research team reported in December 2007 in Nutrition & Metabolism that pre-germinated brown rice was better at protecting nerves from diabetes than un-soaked brown or white rice. They showed a then-unidentified lipid helped protect the nerve membrane and increase activity of HTase and the good cholesterol. Germination also is known to increase levels of the neurotransmitter GABA, which is believed to have many beneficial health effects such as lowering blood pressure, improving cognition and lowering blood glucose levels. However the MCG scientists have shown the lipid has a more powerful impact on HTase activity.

The germ layer activated by soaking brown rice contains many vitamins and minerals in addition to the bioactive ingredient that would be beneficial to everyone, Dr. Yu says.  The roughage of the rice grain also is helpful.


Story Source:

The above story is based on materials provided by Medical College of Georgia. Note: Materials may be edited for content and length.


Cite This Page:

Medical College of Georgia. "Compound That Helps Rice Grow Reduces Nerve, Vascular Damage From Diabetes." ScienceDaily. ScienceDaily, 30 July 2008. <www.sciencedaily.com/releases/2008/07/080728192817.htm>.
Medical College of Georgia. (2008, July 30). Compound That Helps Rice Grow Reduces Nerve, Vascular Damage From Diabetes. ScienceDaily. Retrieved March 29, 2015 from www.sciencedaily.com/releases/2008/07/080728192817.htm
Medical College of Georgia. "Compound That Helps Rice Grow Reduces Nerve, Vascular Damage From Diabetes." ScienceDaily. www.sciencedaily.com/releases/2008/07/080728192817.htm (accessed March 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) — The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) — In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins