Featured Research

from universities, journals, and other organizations

New Approach To Treating Cystic Fibrosis Lung Infection Shows Promise

Date:
September 23, 2008
Source:
Canadian Cystic Fibrosis Foundation
Summary:
Researchers have found a new method of fighting severe lung infections in people with cystic fibrosis.

Researchers at the University of Calgary have found a new method of fighting severe lung infections in people with cystic fibrosis (CF).

Communities of bacteria grow in the lungs of people with CF. Pseudomonas aeruginosa is a common bacterium found in these communities and is often associated with severe lung infections. Pseudomonas represents a constant and ever present threat to the health of people with CF.

Dr. Michael Surette, Professor of Medicine at the University of Calgary, and his team, working with Dr. Harvey Rabin and the Calgary Adult CF Clinic have found that a group of previously overlooked and often undetected bacteria in these communities, the Streptococcus milleri group (SMG), compounds the danger of Pseudomonas aeruginosa. These findings were recently published in Proceedings of the National Academy of Science USA.

Currently, doctors have treated Pseudomonas with antibiotics, however, the Pseudomonas family of bacteria is increasingly becoming resistant to treatment. Dr. Surette's research shows clinical benefit simply by treating SMG, and thereby disrupting the bacterial community.

Doctors at the Calgary Adult CF Clinic (Foothills Hospital) have already tested this new approach successfully, with patients admitted to hospital with severe lung infections. People treated with SMG-targeted therapies quickly returned to a stable state.

"This is important new information," said Dr. Michael Surette. "In our small patient group, the laboratory findings have been used to guide treatment, with positive results."

The research project, funded by the Canadian Cystic Fibrosis Foundation, has led to a real alternative to combating severe lung infections in persons with CF. Early study results show that it may also be a treatment option for individuals with chronic lung infections unrelated to CF.

"These findings underline the importance of supporting CF research," said Cathleen Morrison, Chief Executive Officer of the Canadian Cystic Fibrosis Foundation. "In this case, laboratory research has been translated rapidly into actual treatment, helping people with cystic fibrosis fight back against aggressive infections."

About Cystic Fibrosis

Cystic fibrosis, which affects the lungs and the digestive system, is the most common, fatal, genetic disease affecting Canadian children and young adults. In the digestive tract, CF blocks the absorption of adequate nutrients from food. In the lungs, the effects of the disease are most devastating; and with time, respiratory problems become increasingly severe. Ultimately, most CF deaths are due to lung disease.


Story Source:

The above story is based on materials provided by Canadian Cystic Fibrosis Foundation. Note: Materials may be edited for content and length.


Cite This Page:

Canadian Cystic Fibrosis Foundation. "New Approach To Treating Cystic Fibrosis Lung Infection Shows Promise." ScienceDaily. ScienceDaily, 23 September 2008. <www.sciencedaily.com/releases/2008/09/080922174634.htm>.
Canadian Cystic Fibrosis Foundation. (2008, September 23). New Approach To Treating Cystic Fibrosis Lung Infection Shows Promise. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2008/09/080922174634.htm
Canadian Cystic Fibrosis Foundation. "New Approach To Treating Cystic Fibrosis Lung Infection Shows Promise." ScienceDaily. www.sciencedaily.com/releases/2008/09/080922174634.htm (accessed July 30, 2014).

Share This




More Health & Medicine News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Generics Eat Into Pfizer's Sales

Generics Eat Into Pfizer's Sales

Reuters - Business Video Online (July 29, 2014) Pfizer, the world's largest drug maker, cut full-year revenue forecasts because generics could cut into sales of its anti-arthritis drug, Celebrex. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins