Featured Research

from universities, journals, and other organizations

Fungus Lessens Serious Grapefruit-Drug Reaction

Date:
February 5, 2009
Source:
American Chemical Society
Summary:
Scientists in Florida report that adding an edible mushroom-like fungus to grapefruit juice may help to reduce the serious side effects that can occur when people taking certain prescription drugs drink grapefruit juice.

An edible fungus added to grapefruit juice could reduce side effects people have when drinking that juice while taking prescription drugs, scientists report.
Credit: Royal Botanic Gardens, Melbourne

Scientists in Florida report that adding an edible mushroom-like fungus to grapefruit juice may help to reduce the serious side effects that can occur when people taking certain prescription drugs drink grapefruit juice.

Related Articles


In the study, Kyung Myung and colleagues explain that furanocoumarins (FCs) — chemicals found in grapefruit and some other citrus — block a key enzyme critical for metabolizing, or breaking down, certain prescription medications. This “grapefruit/drug” interaction — sometimes called the “grapefruit effect” — can turn normal drug doses into toxic overdoses. Researchers have tried to remove FCs using chemical, physical and microbiological methods. Myung and colleagues, for example, had previously discovered that an inedible fungus can be used to remove most of the FCs from grapefruit juice.

Now they report that the edible fungus Morchella esculenta, which is from the same major fungal group as the previously tested inedible fungus, removed most of the furanocoumarins from the grapefruit juice. It also reduced grapefruit juice’s inhibition of the enzyme by 60 percent.

Dried M. esculenta also worked, leading the researchers to suggest that it could be useful in removing the compound from grapefruit juice and identifying the specific components in the fungi that bind to furanocoumarins.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Myung et al. Removal of Furanocoumarins in Grapefruit Juice by Edible Fungi. Journal of Agricultural and Food Chemistry, January 14, 2009; 56 (24): 12064 DOI: 10.1021/jf802713g

Cite This Page:

American Chemical Society. "Fungus Lessens Serious Grapefruit-Drug Reaction." ScienceDaily. ScienceDaily, 5 February 2009. <www.sciencedaily.com/releases/2009/01/090128214017.htm>.
American Chemical Society. (2009, February 5). Fungus Lessens Serious Grapefruit-Drug Reaction. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2009/01/090128214017.htm
American Chemical Society. "Fungus Lessens Serious Grapefruit-Drug Reaction." ScienceDaily. www.sciencedaily.com/releases/2009/01/090128214017.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins