Featured Research

from universities, journals, and other organizations

Maggot Therapy Similar To Standard Care For Leg Ulcers

Date:
March 23, 2009
Source:
BMJ-British Medical Journal
Summary:
Larval (maggot) therapy has similar health benefits and costs compared with a standard treatment for leg ulcers, find two studies.

Larval (maggot) therapy has similar health benefits and costs compared with a standard treatment for leg ulcers, find two studies published on the British Medical Journal website.

Leg ulcers are chronic wounds most commonly caused by diseased veins in the legs. Debridement (the removal of dead tissue from the ulcer surface) is a common part of ulcer management and is widely viewed as having a role in promoting wound healing.

Debridement can be undertaken with a hydrogel, but it has been suggested that larval therapy debrides wounds more swiftly, as well as stimulating healing and reducing infection.

A team of UK researchers have carried out the first randomised controlled trial to investigate the clinical and cost-effectiveness of larval therapy on wound healing.

The trial involved 267 participants who had at least one venous or mixed venous/arterial leg ulcer with dead tissue (sloughy and/or necrotic tissue) covering at least a quarter of the wound.

Participants were randomised to receive loose larvae, bagged larvae or hydrogel during the debridement phase, followed by standard treatment. People were monitored for up to 12 months, during which time the date of complete healing of the ulcer was recorded by trained nurses.

Date of debridement was also recorded, as were bacterial levels, adverse events and ulcer-related pain. Participants completed a health-related quality of life questionnaire at the start of the study, and then again at three, six, nine and 12 months.

Larval therapy significantly reduced the time to debridement compared with hydrogel, but there was no evidence of a difference in time to ulcer healing (half of patients allocated to the larvae group were healed by 236 days compared with 245 days for the hydrogel group).

There was no difference between larvae and hydrogel groups in health-related quality of life or in bacterial load (including MRSA). Larval therapy was associated with twice as much pain in the 24 hours prior to removal of the first application compared with hydrogel.

The authors conclude that, although larval therapy is a more effective debriding agent than hydrogel, there is no evidence from this trial that it should be recommended for routine use on sloughy leg ulcers with the aim of speeding healing or reducing bacterial load. They suggest that further research is required to explore the relationship between wound debridement, healing and microbiology, and to better understand the value of debridement from the patient perspective.

In a separate analysis, the researchers calculate that larval therapy is likely to have similar cost-effectiveness to hydrogel. As such, they conclude that healthcare decision makers should generally be indifferent when recommending these two therapies for the debridement of sloughy leg ulcers.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Cite This Page:

BMJ-British Medical Journal. "Maggot Therapy Similar To Standard Care For Leg Ulcers." ScienceDaily. ScienceDaily, 23 March 2009. <www.sciencedaily.com/releases/2009/03/090319224534.htm>.
BMJ-British Medical Journal. (2009, March 23). Maggot Therapy Similar To Standard Care For Leg Ulcers. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/2009/03/090319224534.htm
BMJ-British Medical Journal. "Maggot Therapy Similar To Standard Care For Leg Ulcers." ScienceDaily. www.sciencedaily.com/releases/2009/03/090319224534.htm (accessed September 18, 2014).

Share This



More Health & Medicine News

Thursday, September 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Artificial Sweetener Could Promote Diabetes

Artificial Sweetener Could Promote Diabetes

Newsy (Sep. 17, 2014) Doctors once thought artificial sweeteners lacked the health risks of sugar, but a new study says they can impact blood sugar levels the same way. Video provided by Newsy
Powered by NewsLook.com
Ebola Vaccine Trial Gets Underway at Oxford University

Ebola Vaccine Trial Gets Underway at Oxford University

AFP (Sep. 17, 2014) A healthy British volunteer is to become the first person to receive a new vaccine for the Ebola virus after US President Barack Obama called for action against the epidemic and warned it was "spiralling out of control." Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins