Featured Research

from universities, journals, and other organizations

Rhythmic Genomics: The Yeast Metronome And The Walk Of Life

Date:
April 9, 2009
Source:
Institute of Food Research
Summary:
New genome sequence information from the humble baker's yeast has revealed surprising variation in a set of genes that can be thought of as nature's oldest clock. Scientists have shown how ribosomal RNA genes that are essential to all Earth's organisms provide insight into how genomes maintain their integrity on their evolutionary journey.

New genome sequence information from the humble baker’s yeast has revealed surprising variation in a set of genes that can be thought of as nature’s oldest clock. In a paper published in Genome Research scientists show how ribosomal RNA genes that are essential to all Earth's organisms provide insight into how genomes maintain their integrity on their evolutionary journey.

Related Articles


Ribosomal RNA sequence changes have been ticking away like clockwork for over 3 billion years, maybe even pre-dating the origin of the DNA world itself. However, even the slightest changes in sequence of these genes can be fatal. It is vital to conserve the important genetic ‘cogs’ to make sure cells function correctly. However, significant changes do occur, contrary to expectation, and yet the yeast somehow still survives.

Furthermore, when two yeasts hybridise the clocks appear to re-set, apparently overwriting each others’ rhythm and eliminating unwanted variations on the theme. This provides clues as to how key motifs are conserved and allows us to track the evolutionary history of hybrids.

Steve James, lead researcher at the Institute of Food Research (IFR), said "I have sequenced these genes to selectively identify yeast species for over 15 years and had no idea they would turn out to be so variable."

Rob Davey, computational biologist at the National Collection of Yeast Cultures (NCYC), said “we can use new computer techniques to model the changes mathematically and really get to grips with what orchestrates the variation in these important cell housekeepers.”

Ian Roberts, Curator of NCYC, said "Yeasts are everywhere around us in nature and industry. This extra level of detail allows us to resolve important differences between yeasts and gain maximum benefits from their use in food, drink and healthcare."

This work was carried out in collaboration with the Wellcome Trust Sanger Institute and the Massachusetts Institute of Technology. The IFR is an institute of the Biotechnology and Biological Sciences Research Council (BBSRC).


Story Source:

The above story is based on materials provided by Institute of Food Research. Note: Materials may be edited for content and length.


Journal Reference:

  1. James et al. Repetitive sequence variation and dynamics in the ribosomal DNA array of Saccharomyces cerevisiae as revealed by whole-genome resequencing. Genome Research, 2009; 19 (4): 626 DOI: 10.1101/gr.084517.108

Cite This Page:

Institute of Food Research. "Rhythmic Genomics: The Yeast Metronome And The Walk Of Life." ScienceDaily. ScienceDaily, 9 April 2009. <www.sciencedaily.com/releases/2009/04/090407075347.htm>.
Institute of Food Research. (2009, April 9). Rhythmic Genomics: The Yeast Metronome And The Walk Of Life. ScienceDaily. Retrieved November 23, 2014 from www.sciencedaily.com/releases/2009/04/090407075347.htm
Institute of Food Research. "Rhythmic Genomics: The Yeast Metronome And The Walk Of Life." ScienceDaily. www.sciencedaily.com/releases/2009/04/090407075347.htm (accessed November 23, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Sunday, November 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Anglerfish Rarely Seen In Its Habitat Will Haunt You

Anglerfish Rarely Seen In Its Habitat Will Haunt You

Newsy (Nov. 22, 2014) For the first time Monterey Bay Aquarium recorded a video of the elusive, creepy and rarely seen anglerfish. Video provided by Newsy
Powered by NewsLook.com
Birds Around the World Take Flight

Birds Around the World Take Flight

Reuters - Light News Video Online (Nov. 22, 2014) An imperial eagle equipped with a camera spreads its wings over London. It's just one of the many birds making headlines in this week's "animal roundup". Jillian Kitchener reports. Video provided by Reuters
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Raw: Baby Okapi Born at Houston Zoo

Raw: Baby Okapi Born at Houston Zoo

AP (Nov. 20, 2014) The Houston Zoo released video of a male baby okapi. Okapis, also known as the "forest giraffe", are native to the Democratic Republic of the Congo in Central Africa. Video is mute from source. (Nov. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins