Featured Research

from universities, journals, and other organizations

Coordinated Pushback Could Help Contain Bovine Bacterial Diseases

Date:
June 1, 2009
Source:
USDA/Agricultural Research Service
Summary:
Scientists are in a longstanding battle against two serious bacterial infections of livestock: Johne's disease and bovine tuberculosis.

ARS microbiologist Judy Stabel is developing ways to diagnose Johne's Disease in young animals.
Credit: Photo by Peggy Greb

Agricultural Research Service (ARS) scientists at the National Animal Disease Center (NADC) in Ames, Iowa, are in a longstanding battle against two serious bacterial infections of livestock: Johne's disease and bovine tuberculosis.

Related Articles


Experts believe that almost 70 percent of U.S. cattle herds are infected with M. avium subspecies paratuberculosis (MAP), the bacterium that causes Johne's disease. NADC microbiologist John Bannantine and colleagues took information from the MAP genome to assemble an array of 96 proteins. Then they used the array to identify gene sequences that might be useful in confirming a Johne's disease diagnosis, or that might serve as targets for disease intervention and treatment.

Bannantine's team found three proteins that consistently drew the strongest "attacks" from serum antibodies, an immune response that clearly linked the three proteins with the onset of the disease. With additional work, these antigens might provide crucial building blocks for the development of a diagnostic tool for Johne's disease.

Meanwhile, NADC microbiologist Judy Stabel has been studying the early stages of MAP infection and finding ways to diagnose the disease in young animals. She has also helped evaluate animal models for MAP research, and has concluded that a smaller ruminant model-such as goats or sheep-shows promise.

NADC veterinary officers Ray Waters and Mitch Palmer and molecular biologist Tyler Thacker are working on several fronts to optimize bovine tuberculosis diagnostic tests and vaccinations for both wildlife and domestic livestock. For instance, Palmer is using white-tailed deer, which are a significant reservoir of bovine tuberculosis, to test experimental vaccines for potential bovine tuberculosis control in wildlife.

So far his studies indicate that vaccines can be effective in decreasing the severity of the disease, and that oral vaccination appears to be as effective as subcutaneous vaccination. But other safety issues still need to be resolved before the vaccine could be used in wildlife.

The NADC scientists have also been using neonatal calves to test human tuberculosis vaccines. This approach is cheaper and safer to use than testing in nonhuman primates.


Story Source:

The above story is based on materials provided by USDA/Agricultural Research Service. Note: Materials may be edited for content and length.


Cite This Page:

USDA/Agricultural Research Service. "Coordinated Pushback Could Help Contain Bovine Bacterial Diseases." ScienceDaily. ScienceDaily, 1 June 2009. <www.sciencedaily.com/releases/2009/05/090522180257.htm>.
USDA/Agricultural Research Service. (2009, June 1). Coordinated Pushback Could Help Contain Bovine Bacterial Diseases. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2009/05/090522180257.htm
USDA/Agricultural Research Service. "Coordinated Pushback Could Help Contain Bovine Bacterial Diseases." ScienceDaily. www.sciencedaily.com/releases/2009/05/090522180257.htm (accessed October 25, 2014).

Share This



More Plants & Animals News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Reuters - Innovations Video Online (Oct. 24, 2014) Miniature deep sea animals discovered off the Australian coast almost three decades ago are puzzling scientists, who say the organisms have proved impossible to categorise. Academics at the Natural History of Denmark have appealed to the world scientific community for help, saying that further information on Dendrogramma enigmatica and Dendrogramma discoides could answer key evolutionary questions. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Black Bear Cub Goes Sunday Shopping

Black Bear Cub Goes Sunday Shopping

Reuters - Light News Video Online (Oct. 23, 2014) Price check on honey? Bear cub startles Oregon drugstore shoppers. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Dances With Wolves in China's Wild West

Dances With Wolves in China's Wild West

AFP (Oct. 23, 2014) One man is on a mission to boost the population of wolves in China's violence-wracked far west. The animal - symbol of the Uighur minority there - is under threat with a massive human resettlement program in the region. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins