Featured Research

from universities, journals, and other organizations

Infiltrating Blood-derived Macrophages Are Vital Cells In Recovery From Spinal Cord Injury In Mice

Date:
July 27, 2009
Source:
Public Library of Science
Summary:
Although macrophages are known as essential players in wound healing, their contribution to recovery from spinal cord injury is a subject of debate. Using a mouse model of spinal injury, scientists tested the effect of macrophages on the recovery process after injury.

Although macrophages are known as essential players in wound healing, their contribution to recovery from spinal cord injury is a subject of debate. Using a mouse model of spinal injury, Michal Schwartz and colleagues from the Weizmann institute of Science, Rehovot, Israel tested the effect of macrophages on the recovery process after injury and demonstrate an important anti-inflammatory role for a subset of infiltrating monocyte-derived macrophages that is dependent upon their expression of the anti-inflammatory molecule interleukin-10.

These results suggest that this subset of macrophages may have a beneficial effect on spinal cord injuries.

Funding: MS holds the Maurice and Ilse Katz Professorial Chair in Neuroimmunology. The work was supported in part by the High Q Foundation, an NRSAD award, ERC award, and by IsrALS, given to MS. This work was supported also by the Israel Science Foundation, given to MS and SJ. SJ was supported by the MINERVA Foundation and by a joint ISF Bio-Med research grant, and is the incumbent of the Pauline Recanati Career Development Chair. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Shechter et al. Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice. PLoS Medicine, 2009; 6 (7): e1000113 DOI: 10.1371/journal.pmed.1000113

Cite This Page:

Public Library of Science. "Infiltrating Blood-derived Macrophages Are Vital Cells In Recovery From Spinal Cord Injury In Mice." ScienceDaily. ScienceDaily, 27 July 2009. <www.sciencedaily.com/releases/2009/07/090727203631.htm>.
Public Library of Science. (2009, July 27). Infiltrating Blood-derived Macrophages Are Vital Cells In Recovery From Spinal Cord Injury In Mice. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2009/07/090727203631.htm
Public Library of Science. "Infiltrating Blood-derived Macrophages Are Vital Cells In Recovery From Spinal Cord Injury In Mice." ScienceDaily. www.sciencedaily.com/releases/2009/07/090727203631.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com
$23.6 Billion Awarded To Widow In Smoking Lawsuit

$23.6 Billion Awarded To Widow In Smoking Lawsuit

Newsy (July 20, 2014) Cynthia Robinson claims R.J. Reynolds Tobacco Company hid the health and addiction risks of its products, leading to the death of her husband in 1996. Video provided by Newsy
Powered by NewsLook.com
Tooth Plaque Provides Insight Into Diets Of Ancient People

Tooth Plaque Provides Insight Into Diets Of Ancient People

Newsy (July 19, 2014) Research on plaque from ancient teeth shows that our prehistoric ancestor's had a detailed understanding of plants long before developing agriculture. Video provided by Newsy
Powered by NewsLook.com
Contaminated Water Kills 3 Babies in South African Town

Contaminated Water Kills 3 Babies in South African Town

AFP (July 18, 2014) Contaminated water in South Africa's northwestern town of Bloemhof kills three babies and hospitalises over 500 people. The incident highlights growing fears over water safety in South Africa. Duration: 02:22 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins