Featured Research

from universities, journals, and other organizations

Oral Vaccine May Reduce Exacerbations in Patients with COPD

Date:
April 13, 2010
Source:
American College of Chest Physicians
Summary:
A novel vaccine may help reduce the number and severity of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD).

A novel vaccine may help reduce the number and severity of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD).

Australian researchers developed a new oral immunotherapy (HI-164OV) using Haemophilus influenzae, the bacteria causing meningitis in children. In a randomized, multicenter, double blind, placebo-controlled trial, researchers tested the efficacy of the new vaccine and its effects on outcomes in 38 patients with severe COPD.

Results showed significant reductions in the areas of moderate to severe exacerbations (63 percent reduction), mean duration of episode (37 percent reduction), prescribed antibiotics (56 percent reduction), and exacerbations requiring hospital admission (90 percent reduction). No specific adverse effect was detected.

Researchers conclude that the vaccine shows potential in improving the health of patients with COPD.

The article is published in the April issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians.


Story Source:

The above story is based on materials provided by American College of Chest Physicians. Note: Materials may be edited for content and length.


Journal Reference:

  1. M. K. Tandon, M. Phillips, G. Waterer, M. Dunkley, P. Comans, R. Clancy. Oral Immunotherapy with inactivated NTHi reduces severity of acute exacerbations in severe COPD. Chest, 2009; DOI: 10.1378/chest.09-1382

Cite This Page:

American College of Chest Physicians. "Oral Vaccine May Reduce Exacerbations in Patients with COPD." ScienceDaily. ScienceDaily, 13 April 2010. <www.sciencedaily.com/releases/2010/04/100406160430.htm>.
American College of Chest Physicians. (2010, April 13). Oral Vaccine May Reduce Exacerbations in Patients with COPD. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2010/04/100406160430.htm
American College of Chest Physicians. "Oral Vaccine May Reduce Exacerbations in Patients with COPD." ScienceDaily. www.sciencedaily.com/releases/2010/04/100406160430.htm (accessed August 20, 2014).

Share This




More Health & Medicine News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Freetown a City on Edge

Ebola-Hit Sierra Leone's Freetown a City on Edge

AFP (Aug. 19, 2014) Residents of Sierra Leone's capital voice their fears as the Ebola virus sweeps through west Africa. Duration: 00:56 Video provided by AFP
Powered by NewsLook.com
101-Year-Old Working Man Has All The Advice You Need

101-Year-Old Working Man Has All The Advice You Need

Newsy (Aug. 19, 2014) Herman Goldman has worked at the same lighting store for almost 75 years. Find out his secrets to a happy, productive life. Video provided by Newsy
Powered by NewsLook.com
Researcher Testing on-Field Concussion Scanners

Researcher Testing on-Field Concussion Scanners

AP (Aug. 19, 2014) Four Texas high school football programs are trying out an experimental system designed to diagnose concussions on the field. The technology is in response to growing concern over head trauma in America's most watched sport. (Aug. 19) Video provided by AP
Powered by NewsLook.com
American Ebola Patient Apparently Improving, Outbreak Is Not

American Ebola Patient Apparently Improving, Outbreak Is Not

Newsy (Aug. 19, 2014) Nancy Writebol, an American missionary who contracted Ebola, is apparently getting better, according to her husband. The outbreak, however, is not. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins