Featured Research

from universities, journals, and other organizations

Adults with newly diagnosed diabetes at risk of liver disease, study finds

Date:
June 29, 2010
Source:
Canadian Medical Association Journal
Summary:
Adults with newly diagnosed diabetes are at higher long-term risk of serious liver disease, including cirrhosis and liver failure, according to a new study.

Adults with newly diagnosed diabetes are at higher long-term risk of serious liver disease, including cirrhosis and liver failure, according to a research article published in CMAJ Canadian Medical Association Journal.

The negative impact of diabetes on the eye, kidney and blood vessels is well-known, but little is known about its effect on the liver.

A study conducted over 13 years by researchers from St. Michael's Hospital, University of Toronto and the Institute for Clinical Evaluative Sciences in Toronto included 438 069 adults aged 30 to 75 years with newly diagnosed diabetes over a 13 year period and a comparable group of 2 059 709 people without diabetes. They found an incidence rate of 8 per 10 000 person-years for serious liver disease in people with newly diagnosed diabetes compared to a rate of 4 per 10 000 person years among non-diabetic controls. They note that persons with diabetes and concomitant obesity or hypertension had the highest risk of liver disease.

"We posit that the presence of overt diabetes reflects more severe insulin resistance, a greater fatty load in the liver and potentially worse hepatic inflammation and injury," write Drs. Joel Ray and Gillian Booth of St. Michael's Hospital. "Those who have diabetes may not just have higher blood sugars, but greater long-term insulin resistance and fatty load to the liver, which ultimately impacts on the integrity of the liver's cells."

A previous study by the US Department of Veterans Affairs found that the incidence of serious liver disease was two times higher in people with diabetes, although the study sample comprised older men in hospital.

The authors suggest that the effects of weight loss and glycemic and lipid control should be better understood before instituting annual screening for liver disease.


Story Source:

The above story is based on materials provided by Canadian Medical Association Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. Liane Porepa, Joel G Ray, Paula Sanchez-Romeu, Gillian L Booth. Newly diagnosed diabetes mellitus as a risk factor for serious liver disease. Canadian Medical Association Journal, 2010; DOI: 10.1503/cmaj.092144

Cite This Page:

Canadian Medical Association Journal. "Adults with newly diagnosed diabetes at risk of liver disease, study finds." ScienceDaily. ScienceDaily, 29 June 2010. <www.sciencedaily.com/releases/2010/06/100621121350.htm>.
Canadian Medical Association Journal. (2010, June 29). Adults with newly diagnosed diabetes at risk of liver disease, study finds. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2010/06/100621121350.htm
Canadian Medical Association Journal. "Adults with newly diagnosed diabetes at risk of liver disease, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/06/100621121350.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins