Featured Research

from universities, journals, and other organizations

Can START stop cholesterol build-up?

Date:
June 24, 2010
Source:
The Biochemical Society
Summary:
A newly discovered group of proteins could help treat cholesterol build-up in arteries.

A newly discovered group of proteins could help treat cholesterol build-up in arteries.

This build-up leads to atherosclerosis or 'hardening of the arteries', and the resulting condition, coronary heart disease, kills an estimated 124,000 each year in England and Wales.

In a paper in the latest issue of Clinical Science, Annette Graham and colleagues at Glasgow Caledonian University report on the use of steroidogenic acute regulatory protein-related lipid transfer (START) proteins to remove excess cholesterol from macrophage foam cells (cells that form obstacles in the arteries) and stop atherosclerotic lesions growing and even shrink them.

The most promising protein in the START family is STARD3 and this will be used in further experiments to see if it can form the basis for a therapy which will reduce cholesterol synthesis and build-up.


Story Source:

The above story is based on materials provided by The Biochemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Faye Borthwick, Anne-Marie Allen, JaniceM. Taylor, Annette Graham. Overexpression of STARD3 in human monocyte/macrophages induces an anti-atherogenic lipid phenotype. Clinical Science, 2010; 119 (7): 265 DOI: 10.1042/CS20100266

Cite This Page:

The Biochemical Society. "Can START stop cholesterol build-up?." ScienceDaily. ScienceDaily, 24 June 2010. <www.sciencedaily.com/releases/2010/06/100623085843.htm>.
The Biochemical Society. (2010, June 24). Can START stop cholesterol build-up?. ScienceDaily. Retrieved September 23, 2014 from www.sciencedaily.com/releases/2010/06/100623085843.htm
The Biochemical Society. "Can START stop cholesterol build-up?." ScienceDaily. www.sciencedaily.com/releases/2010/06/100623085843.htm (accessed September 23, 2014).

Share This



More Health & Medicine News

Tuesday, September 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins