Featured Research

from universities, journals, and other organizations

Bioengineers develop bacterial strain to increase ethanol biofuel production

Date:
December 10, 2010
Source:
Wiley-Blackwell
Summary:
Bioengineers have modified a strain of bacteria to increase its ability to produce ethanol. The research reveals how adaptation and metabolic engineering can be combined for strain improvement, a positive development for the biofuel industry.

A team of bioengineers in the United States has modified a strain of bacteria to increase its ability to produce ethanol. The research, published in Biotechnology and Bioengineering, reveals how adaptation and metabolic engineering can be combined for strain improvement, a positive development for the biofuel industry.

Related Articles


The team focused their research on Zymomonas mobilis, a bacterium noted for its bio-ethanol producing potential. However, the team believed that ethanol production could be increased through improvement of xylose fermentation.

"Zymomonas mobilis is a superb ethanol producer with productivity exceeding yeast strains by several fold," said lead author Rachel Chen from the Georgia Institute of Technology. "In this study we sought to improve ethanol production by enhancing the ability of Z. mobilis to use and ferment xylose. Fermenting xylose at high concentration could in turn increase ethanol concentration, resulting in much improved productivity."

The team found that by metabolically altering the strain, sugar fermentation time was reduced from over 110 hours to about 35 hours. This improvement in fermentation allowed the strain to ferment higher concentrations of xylose.

"This demonstrated increase in fermentation and xylose utilization enabled us to produce ethanol to a concentration of 9% (w/v), the highest ever shown for this organism in mixed sugar fermentation," said Chen.

This research also investigated the underlying mechanism for the improvement. Interestingly, by adapting a strain in a high concentration of xylose, significant alterations of metabolism occurred.

One noticeable change was reduced levels of xylitol, a byproduct of xylose fermentation which can inhibit the strain's xylose metabolism. In addition, the first step of xylose metabolism, believed to be the rate-limiting step, was accelerated 4-8 times in the adapted strain, with the net effect of channeling xylose to ethanol instead of xylitol.

"This research illustrates the power of adaptation in strain improvement," concluded Chen. "This confirms that xylitol metabolism is the key to efficient use of xylose in this bacterium, which in turn can be vital for producing ethanol. This shows that adaptation is not only useful in improving strains, but is equally useful for pinpointing key bottlenecks in metabolically engineered strains."


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. Agrawal. M, Mao. Z, Chen. R. Adaptation yields a highly efficient xylose-fermenting Zymomonas mobilis strain. Biotechnology and Bioengineering, December 2010 DOI: 10.1002/bit.23021

Cite This Page:

Wiley-Blackwell. "Bioengineers develop bacterial strain to increase ethanol biofuel production." ScienceDaily. ScienceDaily, 10 December 2010. <www.sciencedaily.com/releases/2010/12/101209201940.htm>.
Wiley-Blackwell. (2010, December 10). Bioengineers develop bacterial strain to increase ethanol biofuel production. ScienceDaily. Retrieved April 19, 2015 from www.sciencedaily.com/releases/2010/12/101209201940.htm
Wiley-Blackwell. "Bioengineers develop bacterial strain to increase ethanol biofuel production." ScienceDaily. www.sciencedaily.com/releases/2010/12/101209201940.htm (accessed April 19, 2015).

Share This


More From ScienceDaily



More Matter & Energy News

Sunday, April 19, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

At Least 15 Injured in a California Natural Gas Pipeline Explosion

At Least 15 Injured in a California Natural Gas Pipeline Explosion

Reuters - US Online Video (Apr. 18, 2015) At least 15 injred after natural gas transmission line ruptures in Fresno, California. Julie Noce reports. Video provided by Reuters
Powered by NewsLook.com
NASA Electric Rover Goes for a Spin

NASA Electric Rover Goes for a Spin

Reuters - Innovations Video Online (Apr. 17, 2015) NASA&apos;s prototype electric buggy could influence future space rovers and conventional cars. Jim Drury reports. Video provided by Reuters
Powered by NewsLook.com
Scientists Create Self-Powering Camera

Scientists Create Self-Powering Camera

Reuters - Innovations Video Online (Apr. 17, 2015) American scientists build a self-powering camera that captures images without using an external power source, allowing it to operate indefinitely in a well-lit environment. Elly Park reports. Video provided by Reuters
Powered by NewsLook.com
The State Of Virtual Reality

The State Of Virtual Reality

Newsy (Apr. 17, 2015) Virtual Reality is still a young industry. What’s on offer and what should we expect from our immersive new future? Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins