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Cause of stress-related DNA damage pinpointed: Findings suggest new model for developing novel therapeutic approaches

Date:
August 22, 2011
Source:
Scripps Research Institute
Summary:
Sscientists have helped identify a molecular pathway that plays a key role in stress-related damage to the genome, the entirety of an organism's hereditary information.

Working closely with a team of researchers from Duke University, scientists from the Florida campus of The Scripps Research Institute have helped identify a molecular pathway that plays a key role in stress-related damage to the genome, the entirety of an organism's hereditary information.


Story Source:

The above story is based on materials provided by Scripps Research Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. Makoto R. Hara, Jeffrey J. Kovacs, Erin J. Whalen, Sudarshan Rajagopal, Ryan T. Strachan, Wayne Grant, Aaron J. Towers, Barbara Williams, Christopher M. Lam, Kunhong Xiao, Sudha K. Shenoy, Simon G. Gregory, Seungkirl Ahn, Derek R. Duckett, Robert J. Lefkowitz. A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. Nature, 2011; DOI: 10.1038/nature10368

Cite This Page:

Scripps Research Institute. "Cause of stress-related DNA damage pinpointed: Findings suggest new model for developing novel therapeutic approaches." ScienceDaily. ScienceDaily, 22 August 2011. <www.sciencedaily.com/releases/2011/08/110822151024.htm>.
Scripps Research Institute. (2011, August 22). Cause of stress-related DNA damage pinpointed: Findings suggest new model for developing novel therapeutic approaches. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2011/08/110822151024.htm
Scripps Research Institute. "Cause of stress-related DNA damage pinpointed: Findings suggest new model for developing novel therapeutic approaches." ScienceDaily. www.sciencedaily.com/releases/2011/08/110822151024.htm (accessed April 24, 2014).

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At Last, a Reason Why Stress Causes DNA Damage

Aug. 21, 2011 For years, researchers have published papers that associate chronic stress with chromosomal damage. Now researchers have discovered a mechanism that helps to explain the stress response in terms of ... read more
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