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Stopping dengue fever with bacteria and math

Date:
August 29, 2011
Source:
University of Chicago Press Journals
Summary:
It may be possible to eliminate the deadly dengue fever by infecting mosquitoes with a bacterium called Wolbachia that prevents the mosquitoes from transmitting the dengue virus to humans. A new mathematical model may be helpful in getting the bacteria established in mosquito populations.
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It may be possible to eliminate the deadly dengue fever by infecting mosquitoes with a bacterium called Wolbachia that prevents the mosquitoes from transmitting the dengue virus to humans. A new mathematical model, developed by Nick Barton (Institute of Science and Technology, Austria) and Michael Turelli (University of California, Davis), may be helpful in getting the bacteria established in mosquito populations.

"Mathematical analyses are central to successfully deploying this novel method of disease control," said Turelli, who is a co-primary investigator on the Eliminate Dengue Program. "Our analysis describes the conditions that allow researchers to initiate spreading waves, approximate the expected wave speed, and describe conditions -- specifically, variation in population density -- that will halt their spread."

The model predicts that releases of dengue-blocking bacteria over roughly one square kilometer should suffice to initiate a traveling wave of mosquito infection in urban areas. The first successful field release of Wolbachia in Australia are reported in the current issue of Nature.

The research appears in the September 2011 issue of the The American Naturalist, published by The University of Chicago Press for The American Society of Naturalists.


Story Source:

The above post is reprinted from materials provided by University of Chicago Press Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. N. H. Barton, Michael Turelli. Spatial Waves of Advance with Bistable Dynamics: Cytoplasmic and Genetic Analogues of Allee Effects. The American Naturalist, 2011; 178 (3): E48 DOI: 10.1086/661246

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University of Chicago Press Journals. "Stopping dengue fever with bacteria and math." ScienceDaily. ScienceDaily, 29 August 2011. <www.sciencedaily.com/releases/2011/08/110828210837.htm>.
University of Chicago Press Journals. (2011, August 29). Stopping dengue fever with bacteria and math. ScienceDaily. Retrieved July 6, 2015 from www.sciencedaily.com/releases/2011/08/110828210837.htm
University of Chicago Press Journals. "Stopping dengue fever with bacteria and math." ScienceDaily. www.sciencedaily.com/releases/2011/08/110828210837.htm (accessed July 6, 2015).

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