Featured Research

from universities, journals, and other organizations

Lift weights, eat mustard, build muscles?

Date:
October 6, 2011
Source:
Federation of American Societies for Experimental Biology
Summary:
If you want to lean out, add muscle and get ripped, new research suggests to look to your garden for help. Scientists have found that when a specific plant steroid was ingested by rats, it triggered a response similar to anabolic steroids with minimal side effects. The stimulatory effect of homobrassinolide on protein synthesis in muscle cells led to increases in lean body mass, muscle mass, and physical performance.

If you are looking to lean out, add muscle mass, and get ripped, a new research report published in The FASEB Journal suggests that you might want to look to your garden for a little help. That's because scientists have found that when a specific plant steroid was given orally to rats, it triggered a response similar to anabolic steroids, with minimal side effects. In addition, the research found that the stimulatory effect of homobrassinolide (a type of brassinosteroid found in plants such as mustards) on protein synthesis in muscle cells led to increases in lean body mass, muscle mass and physical performance.

"We hope that one day brassinosteroids may provide an effective, natural, and safe alternative for age- and disease-associated muscle loss, or be used to improve endurance and physical performance," said Slavko Komarnytsky, Ph.D., a researcher involved in the work from the Plants for Human Health Institute, FBNS at North Carolina State University in Kannapolis, N.C. "Because some plants we eat contain these compounds, like mustards, in the future we may be able to breed or engineer these plants for higher brassinosteroid content, thus producing functional foods that can treat or prevent diseases and increase physical performance."

To make this discovery, Komarnytsky and colleagues exposed rat skeletal muscle cells to different amounts of homobrassinolide and measured protein synthesis in cell culture. The result was increased protein synthesis and decreased protein degradation in these cells. Healthy rats then received oral administration of homobrassinolide daily for 24 days. Changes in body weight, food consumption, and body composition were measured. Rats receiving homobrassinolide gained more weight and slightly increased their food intake. Body composition was measured using dual-emission X-ray absorptiometry analysis and showed increased lean body mass in treated animals over those who were not treated. This study was repeated in rats fed high protein diet and similar results were observed. Additionally, researchers used surgically castrated peri-pubertal rat models to examine the ability of homobrassinolide to restore androgen-dependent tissues after androgen deprivation following castration. Results showed increased grip strength and an increase in the number and size of muscle fibers crucial for increased physical performance.

"The temptation is to see this discovery as another quick fix to help you go from fat to fit," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal, "and to a very small degree, this may be true. In reality, however, this study identifies an important drug target for a wide range of conditions that cause muscle wasting."


Story Source:

The above story is based on materials provided by Federation of American Societies for Experimental Biology. Note: Materials may be edited for content and length.


Journal Reference:

  1. D. Esposito, S. Komarnytsky, S. Shapses, I. Raskin. Anabolic effect of plant brassinosteroid. The FASEB Journal, 2011; 25 (10): 3708 DOI: 10.1096/fj.11-181271

Cite This Page:

Federation of American Societies for Experimental Biology. "Lift weights, eat mustard, build muscles?." ScienceDaily. ScienceDaily, 6 October 2011. <www.sciencedaily.com/releases/2011/09/110929103216.htm>.
Federation of American Societies for Experimental Biology. (2011, October 6). Lift weights, eat mustard, build muscles?. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2011/09/110929103216.htm
Federation of American Societies for Experimental Biology. "Lift weights, eat mustard, build muscles?." ScienceDaily. www.sciencedaily.com/releases/2011/09/110929103216.htm (accessed September 19, 2014).

Share This



More Health & Medicine News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com
What HealthKit Bug Means For Your iOS Fitness Apps

What HealthKit Bug Means For Your iOS Fitness Apps

Newsy (Sep. 18, 2014) Apple has delayed the launch of the HealthKit app platform, citing a bug. Video provided by Newsy
Powered by NewsLook.com
U.S. Food Makers Surpass Calorie-Cutting Pledge

U.S. Food Makers Surpass Calorie-Cutting Pledge

Newsy (Sep. 18, 2014) Sixteen large food and beverage companies in the United States that committed to cut calories in their products far surpassed their target. Video provided by Newsy
Powered by NewsLook.com
Residents Vaccinated as Haiti Fights Cholera Epidemic

Residents Vaccinated as Haiti Fights Cholera Epidemic

AFP (Sep. 18, 2014) Haitians receive the second dose of the vaccine against cholera as part of the UN's vaccination campaign. Duration: 00:34 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins