Featured Research

from universities, journals, and other organizations

First monkey exome sequencing platform for biomedical developed

Date:
October 11, 2011
Source:
Beijing Genomics Institute
Summary:
The first exome sequencing platform for the monkey, based on next-generation sequencing technology and monkey exome capturing array, has been developed.

BGI, the world's largest genomics organization, has developed the first exome sequencing platform for the monkey, based on next-generation sequencing technology and monkey exome capturing array (MECA). MECA is a proprietary exome capture array designed by BGI for capturing the entire monkey exome. The combination of this revolutionary array and BGI's high-throughput sequencing technology not only can simplify the workflow of exome sequencing experiments, but also improve cost-effectiveness and turnaround time.

Due to its close relationship genetically and physiologically to humans, the monkey is the most extensively used non-human primate in biomedical research and animal models for human disease research. Macaque monkeys, in particular, are commonly used in research. Each year, there are thousands of Macaques used in pre-clinical studies throughout the world, including studies of pathogenic mechanisms, drug selection, drug dosage, treatment duration and adverse drug reactions, among others.

"Considering the important significance of studying the genetic variations of Macaque monkeys, we initiated the Chinese rhesus macaque (Macaca mulatta) genome project and Cynomolgus macaque (Macaca fascicularis) genome project," said Jiong Zhang, Technical Specialist at BGI. "Based on the genomic data generated from the two projects, BGI designed the exome capture array and developed the exome sequencing platform for the monkey to facilitate biomedical research."

Utilizing the monkey exome sequencing platform, researchers can access genomic regions of interest in their sequencing experiments. "The unique combination of MECA and next-generation sequencing allows researchers to understand efficiently the detailed genetics of monkeys. We believe our breakthrough will enable monkey exome sequencing to play a more important role in biomedical and evolutionary studies," Zhang added.


Story Source:

The above story is based on materials provided by Beijing Genomics Institute. Note: Materials may be edited for content and length.


Cite This Page:

Beijing Genomics Institute. "First monkey exome sequencing platform for biomedical developed." ScienceDaily. ScienceDaily, 11 October 2011. <www.sciencedaily.com/releases/2011/10/111011121246.htm>.
Beijing Genomics Institute. (2011, October 11). First monkey exome sequencing platform for biomedical developed. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2011/10/111011121246.htm
Beijing Genomics Institute. "First monkey exome sequencing platform for biomedical developed." ScienceDaily. www.sciencedaily.com/releases/2011/10/111011121246.htm (accessed July 30, 2014).

Share This




More Plants & Animals News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Raw: Otters Enjoy Water Slides at Japan Zoo

Raw: Otters Enjoy Water Slides at Japan Zoo

AP (July 30, 2014) — River otters were hitting the water slides to beat the summer heatwave on Wednesday at Ichikawa City's Zoological and Botanical Garden. (July 30) Video provided by AP
Powered by NewsLook.com
In Virginia, the Rise of a New Space Coast

In Virginia, the Rise of a New Space Coast

AP (July 30, 2014) — Every summer, tourists make the pilgrimage to Chincoteague Island, Va. to see wild ponies cross the Assateague Channel. But, it's the rockets sending to supplies to the International Space Station that are making this a year-round destination. (July 30) Video provided by AP
Powered by NewsLook.com
Rodents Rampant in Gardens Around Louvre

Rodents Rampant in Gardens Around Louvre

AP (July 29, 2014) — Food scraps and other items left on the grounds by picnickers brings unwelcome visitors to the grounds of the world famous and popular Louvre Museum in Paris. (July 29) Video provided by AP
Powered by NewsLook.com
Jane Goodall Warns Great Apes Face Extinction

Jane Goodall Warns Great Apes Face Extinction

AFP (July 29, 2014) — The world's great apes face extinction within decades, renowned chimpanzee expert Jane Goodall warned Tuesday in a call to arms to ensure man's closest relatives are not wiped out. Duration: 00:58 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins