Featured Research

from universities, journals, and other organizations

Screening technique uncovers five new plant activator compounds

Date:
September 11, 2012
Source:
RIKEN
Summary:
A new high-throughput screening technique has been used to uncover five novel immune-priming compounds in Arabidopsis plants. Discovery of the compounds, which enhance disease resistance without impacting plant growth or crop yield, establishes the new technique as a powerful asset in the battle to protect crops from damaging pathogens.

A new high-throughput screening technique developed by researchers at the RIKEN Plant Science Center (PSC) has been used to uncover five novel immune-priming compounds in Arabidopsis plants. Discovery of the compounds, which enhance disease resistance without impacting plant growth or crop yield, establishes the new technique as a powerful asset in the battle to protect crops from damaging pathogens.

Plant activators, compounds that activate a plant's immune system in response to invasion by pathogens, play a crucial role in crop survival by triggering a range of immune responses. Unlike pesticides, plant activators are not pathogen specific and also not affected by drug resistance, making them ideal for use in agriculture. Wet-rice farmers across East Asia use plant activators as a sustainable means to enhance crop durability without the environmental consequences of microbial pesticides.

One of the key problems of plant activators, however, is that the activation of plant responses they trigger is often associated with arrested growth and reductions in crop yield. Determining why this is so is difficult because despite their widespread use, the molecular mechanisms governing how plant activators work are largely unknown.

The new screening technique developed by the PSC team overcomes this challenge by distinguishing between compounds that induce immune responses on their own from those that do so exclusively in the presence of a pathogen. The former class of compounds, which includes known plant activators, can be toxic to cells and was thus eliminated in the screening. The resulting five compounds, identified from a total of 10,000 compounds screened, enhance resistance against pathogenic Pseudomonas bacteria by priming immune response without directly activating defense genes.

Further investigation revealed that the five compounds inhibit two enzymes that inactivate the defense hormone salicylic acid (SA glucosyltransferases or SAGTs), and gene knockout experiments confirmed that plants without these enzymes exhibit enhanced disease resistance. Together, the results establish the effectiveness of the new technique for finding useful plant activators and the power of SA metabolism as a strategy for crop protection.


Story Source:

The above story is based on materials provided by RIKEN. Note: Materials may be edited for content and length.


Journal Reference:

  1. Y. Noutoshi, M. Okazaki, T. Kida, Y. Nishina, Y. Morishita, T. Ogawa, H. Suzuki, D. Shibata, Y. Jikumaru, A. Hanada, Y. Kamiya, K. Shirasu. Novel Plant Immune-Priming Compounds Identified via High-Throughput Chemical Screening Target Salicylic Acid Glucosyltransferases in Arabidopsis. The Plant Cell, 2012; DOI: 10.1105/tpc.112.098343

Cite This Page:

RIKEN. "Screening technique uncovers five new plant activator compounds." ScienceDaily. ScienceDaily, 11 September 2012. <www.sciencedaily.com/releases/2012/09/120911091351.htm>.
RIKEN. (2012, September 11). Screening technique uncovers five new plant activator compounds. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2012/09/120911091351.htm
RIKEN. "Screening technique uncovers five new plant activator compounds." ScienceDaily. www.sciencedaily.com/releases/2012/09/120911091351.htm (accessed August 1, 2014).

Share This




More Plants & Animals News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com
Visitors Feel Part of the Pack at Wolf Preserve

Visitors Feel Part of the Pack at Wolf Preserve

AP (July 31, 2014) Seacrest Wolf Preserve on the northern Florida panhandle allows more than 10,000 visitors each year to get up close and personal with Arctic and British Columbian Wolves. (July 31) Video provided by AP
Powered by NewsLook.com
Florida Panther Rebound Upsets Ranchers

Florida Panther Rebound Upsets Ranchers

AP (July 31, 2014) With Florida's panther population rebounding, some ranchers complain the protected predators are once again killing their calves. (July 31) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins