Featured Research

from universities, journals, and other organizations

The effect of stress on Atlantic salmon's congenital immunity to IPN

Date:
January 2, 2013
Source:
Norwegian School of Veterinary Science
Summary:
Stress affects the congenital immune defence system. New doctoral research has revealed how stress can lower the immunity of salmon and increase its susceptibility to viral infection. Furthermore, stress can increase the propagation of viruses in the fish's internal organs and can cause "benign" viruses to turn "pernicious".

Fish with IPN.
Credit: Bård Skjelstad

Stress affects the congenital immune defence system. New doctoral research has revealed how stress can lower the immunity of salmon and increase its susceptibility to viral infection. Furthermore, stress can increase the propagation of viruses in the fish's internal organs and can cause "benign" viruses to turn "pernicious."

Koestan Gadan has studied the consequences of stress on the innate immune defence system of the salmon and how it makes the fish more susceptible to disease. She chose the IPN virus (infectious pancreatic necrosis) as a model virus for her research. IPN is the cause of considerable losses in Norwegian salmon farming and has for many years been the most frequently diagnosed disease for this fish.

Up until now, there has been little documentation of how different environmental factors affect salmon's immune defence system. Changes in temperature and salinity, too much or too little oxygen in the water, pollution and physical handling are all sources of stress for these fish. The same applies to normal physiological changes such as for example smoltification, i.e. the way the fish prepares itself for the transition from fresh to seawater.

Gadan discovered that these stress factors lead to increased production of the stress hormone cortisol in the fish. This increase in the level of cortisol affects the immune system of the fish and weaker immunity makes them more susceptible to infections. The fact that stress can trigger an outbreak of IPN is corroborated by the experiences of many in the field. Gadan's research shows that various environmental factors are stressful to the fish, in turn triggering an increase in the level of cortisol in the blood and causing harm to their congenital immune defence system, which is essential to their capacity to ward off viral infections.

Gadan also demonstrated that chronic stress leads to a high level of cortisol over time, which results in increased mortality, a high propagation of viruses and chronic infections. For the first time, she was able to prove that when infected salmon fry were exposed to stress, otherwise benign variants of the IPN virus changed into pathogenic viruses. In other words, stress lowers resistance, increases the "production" of IPN virus in the fish's internal organs and can lead to benign viruses changing into pernicious variants of the virus.


Story Source:

The above story is based on materials provided by Norwegian School of Veterinary Science. Note: Materials may be edited for content and length.


Cite This Page:

Norwegian School of Veterinary Science. "The effect of stress on Atlantic salmon's congenital immunity to IPN." ScienceDaily. ScienceDaily, 2 January 2013. <www.sciencedaily.com/releases/2013/01/130102083557.htm>.
Norwegian School of Veterinary Science. (2013, January 2). The effect of stress on Atlantic salmon's congenital immunity to IPN. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2013/01/130102083557.htm
Norwegian School of Veterinary Science. "The effect of stress on Atlantic salmon's congenital immunity to IPN." ScienceDaily. www.sciencedaily.com/releases/2013/01/130102083557.htm (accessed October 20, 2014).

Share This



More Plants & Animals News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

White Lion Cubs Born in Belgrade Zoo

White Lion Cubs Born in Belgrade Zoo

AFP (Oct. 20, 2014) — Two white lion cubs, an extremely rare subspecies of the African lion, were recently born at Belgrade Zoo. They are being bottle fed by zoo keepers after they were rejected by their mother after birth. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Traditional Farming Methods Gaining Ground in Mali

Traditional Farming Methods Gaining Ground in Mali

AFP (Oct. 20, 2014) — He is leading a one man agricultural revolution in Mali - Oumar Diatabe uses traditional farming methods to get the most out of his land and is teaching others across the country how to do the same. Duration: 01:44 Video provided by AFP
Powered by NewsLook.com
Goliath Spider Will Give You Nightmares

Goliath Spider Will Give You Nightmares

Buzz60 (Oct. 20, 2014) — An entomologist stumbled upon a South American Goliath Birdeater. With a name like that, you know it's a terrifying creepy crawler. Sean Dowling (@SeanDowlingTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Hey, Doc! Sewage, Beer and Food Scraps Can Power Chevrolet’s Bi-Fuel Impala

Hey, Doc! Sewage, Beer and Food Scraps Can Power Chevrolet’s Bi-Fuel Impala

3BL Media (Oct. 20, 2014) — Hey, Doc! Sewage, Beer and Food Scraps Can Power Chevrolet’s Bi-fuel Impala Video provided by 3BL
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins