Featured Research

from universities, journals, and other organizations

Common acne drug not associated with increased risk of IBD

Date:
February 21, 2013
Source:
Child & Family Research Institute
Summary:
Doctors should not be discouraged from prescribing isotretinoin to adolescents for inflammatory acne, according to a new study showing the drug does not increase the risk of inflammatory bowel disease.

Doctors should not be discouraged from prescribing isotretinoin to adolescents for inflammatory acne, according to a new study by Canadian and U.S. scientists showing the drug does not increase the risk of inflammatory bowel disease (IBD).

Related Articles


Led by Dr. Mahyar Etminan of the Child & Family Research Institute at BC Children's Hospital, the Provincial Health Services Authority and the University of British Columbia, the scientists addressed this important drug safety question because of a previous study linking the drug to IBD. In this new report published February 20, 2013 in the medical journal JAMA Dermatology, Dr. Etminan's team says theirs is the first to statistically adjust for severe acne, which is a strong confounding variable that may have led to the overestimation of risk in the earlier study.

The JAMA Dermatology report covered two studies. In one study, the researchers analyzed the health records of a large population of U.S. women between 24-34 years of age. Of the women, 2159 had IBD and 43,180 did not. Only 10 (0.46 per cent) of the women with IBD and only 191 (0.44 per cent) of the women who did not have IBD had used isotretinoin. In the second study, the researchers comprehensively reviewed and analyzed the results of published and unpublished studies. They did not find that isotretinoin increases the risk of IBD.

"We've come to the conclusion that there's no risk that the drug causes inflammatory bowel disease," says Dr. Etminan. "This drug is used for very severe acne that is very traumatic with psychological effects, and it is very effective. Hopefully with this study, it may put dermatologists at ease with prescribing this drug to children and adolescents, knowing that it doesn't cause this adverse effect."

This research was unfunded. Dr. Etminan is a scientist with the Therapeutic Evaluation Unit at the Child & Family Research Institute and the Provincial Health Services Authority. He is appointed in the Faculty of Medicine at the University of British Columbia. The study was co-led by Dr. James Brophy of McGill University.


Story Source:

The above story is based on materials provided by Child & Family Research Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. Mahyar Etminan et al. Isotretinoin and Risk for Inflammatory Bowel DiseaseA Nested Case-Control Study and Meta-analysis of Published and Unpublished DataIsotretinoin and Risk for IBD. JAMA Dermatology, 2013; 149 (2): 216 DOI: 10.1001/jamadermatol.2013.1344

Cite This Page:

Child & Family Research Institute. "Common acne drug not associated with increased risk of IBD." ScienceDaily. ScienceDaily, 21 February 2013. <www.sciencedaily.com/releases/2013/02/130221092004.htm>.
Child & Family Research Institute. (2013, February 21). Common acne drug not associated with increased risk of IBD. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2013/02/130221092004.htm
Child & Family Research Institute. "Common acne drug not associated with increased risk of IBD." ScienceDaily. www.sciencedaily.com/releases/2013/02/130221092004.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) — Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins