Featured Research

from universities, journals, and other organizations

Plant protein shape puzzle solved by molecular 3-D model

Date:
April 15, 2013
Source:
North Carolina State University
Summary:
Researchers believe they have solved a puzzle that has long vexed science. The researchers provide the first three-dimensional model of an enzyme that links a simple sugar, glucose, into long-chain cellulose, the basic building block within plant cell walls that gives plants structure. Cellulose is nature's most abundant renewable biomaterial and an important resource for production of biofuels that represent alternatives to fossil fuels.

The 3-D molecular model of a plant cellulose synthase no longer remains elusive.
Credit: Image courtesy of North Carolina State University

Researchers from North Carolina State University believe they have solved a puzzle that has vexed science since plants first appeared on Earth.

Related Articles


In a groundbreaking paper published online this week in Proceedings of the National Academy of Sciences, the researchers provide the first three-dimensional model of an enzyme that links a simple sugar, glucose, into long-chain cellulose, the basic building block within plant cell walls that gives plants structure. Cellulose is nature's most abundant renewable biomaterial and an important resource for production of biofuels that represent alternatives to fossil fuels.

New understanding of the structure of the modeled plant enzyme, a cellulose synthase, may allow researchers to genetically engineer plants and trees for better cotton fibers or stronger wood, for example. From a materials engineering perspective, the findings can also be used to create beneficial nanocrystals with desired properties and functions.

"This structural model gives us insight into how cellulose synthesis works," said Dr. Yaroslava Yingling, an NC State materials science and engineering professor who is the corresponding author on the study. "In the long term, it could result in new genetically modified plants that can be tweaked to induce specific engineered properties of cellulose."

The study examined the structure of one cellulose synthase found in cotton fibers. The researchers compared their model with the structure of a similar enzyme in bacteria and found that the proteins were similarly folded in key regions required for cellulose synthesis. In the lab rat of the plant family -- Arabidopsis thaliana, or mustard weed -- the researchers identified potential causes for defective cellulose synthesis in mutant plants by making analogies to the modeled cotton cellulose synthase.

"Without the enzyme structure, you can't make strategically designed, rational projections about how to make beneficial changes to the proteins -- but now you can," said Dr. Candace Haigler, an NC State crop scientist and plant biologist who co-authored the study. "In the future we could make cellulose easier to break down into biofuels while ensuring that the plants themselves are able to grow well."

Latsavongsakda Sethaphong, an NC State doctoral student, co-authored the study, as did researchers from Penn State University, the University of Virginia, the University of Ontario Institute of Technology and the University of Kentucky. The computational research was supported as part of The Center for LignoCellulose Structure and Formation, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science.


Story Source:

The above story is based on materials provided by North Carolina State University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Latsavongsakda Sethaphong, Candace H. Haigler, Yaroslava G. Yingling, James D. Kubicki, Jochen Zimmer, Dario Bonetta, Seth DeBolt. Tertiary Model of a Plant Cellulose Synthase. PNAS, April 15, 2013

Cite This Page:

North Carolina State University. "Plant protein shape puzzle solved by molecular 3-D model." ScienceDaily. ScienceDaily, 15 April 2013. <www.sciencedaily.com/releases/2013/04/130415182505.htm>.
North Carolina State University. (2013, April 15). Plant protein shape puzzle solved by molecular 3-D model. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2013/04/130415182505.htm
North Carolina State University. "Plant protein shape puzzle solved by molecular 3-D model." ScienceDaily. www.sciencedaily.com/releases/2013/04/130415182505.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Dinosaur Species Found in Museum Collection

New Dinosaur Species Found in Museum Collection

Reuters - Innovations Video Online (Nov. 27, 2014) A British palaeontologist has discovered a new species of dinosaur while studying fossils in a Canadian museum. Pentaceratops aquilonius was related to Triceratops and lived at the end of the Cretaceous Period, around 75 million years ago. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Classic Hollywood Memorabilia Goes Under the Hammer

Classic Hollywood Memorabilia Goes Under the Hammer

Reuters - Entertainment Video Online (Nov. 26, 2014) The iconic piano from "Casablanca" and the Cowardly Lion suit from "The Wizard of Oz" fetch millions at auction. Sara Hemrajani reports. Video provided by Reuters
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins